Sex-Related Differences in Early In-Hospital Outcome (Technical Success and Complications) of Carotid Artery Stenting and Risk Factors of Carotid Artery Stenosis.

Abstract

Background/objectives: Stroke and arteriosclerotic diseases remain the main challenge for global healthcare. Carotid artery procedures aim to restore blood flow through the carotid arteries to prevent embolic events. The most common techniques include carotid endarterectomy (CEA) and carotid artery stenting (CAS). The choice of intervention depends on the severity of stenosis, the patient's overall condition and the presence of comorbidities. The personalized approach, which includes sex-related differences, is crucial in optimizing the outcome.

Methods: Sex-related differences in atherosclerosis risk factors and early carotid artery stenting treatment outcomes were evaluated in 271 patients. The goal of the study was to asses sex-related differences in early outcome of CAS, including success rate and complications.

Results: The only significant difference in classical arteriosclerosis risk factors included a higher occurrence of smoking among males. The technical success rate of carotid artery stenting was high (94.46%). The sex-related differences in CAS involve using smaller sizes of implanted stents in females. There was a high incidence of complications (mostly minor), predominantly among females. They had a significantly higher frequency of bleeding and hypotension. Blood pressure and BMI significantly influenced the odds of complications.

Conclusions: Females undergoing CAS have a higher complication risk with a similar success rate.