{"title":"Highly Sensitive THz SPR Biosensor Based on Graphene-Coupled Prism Otto Structure.","authors":"Yu Xie, Zean Shen, Mingming Zhang, Mengjiao Ren, Wei Huang, Leyong Jiang","doi":"10.3390/bios15090630","DOIUrl":null,"url":null,"abstract":"<p><p>This study presents a theoretical investigation of a terahertz (THz) surface plasmon resonance (SPR) optical biosensor utilizing a graphene-integrated Otto configuration. Through systematic numerical simulations, we demonstrate that actively modulating graphene's conductivity via an external magnetic field enables tunable SPR behavior with high phase sensitivity. The proposed sensor achieves a phase sensitivity of up to 3.1043×105 deg RIU<sup>-1</sup> in liquid sensing and 2.5854×104 deg RIU<sup>-1</sup> in gas sensing. This simulation-based work establishes a foundational framework for the development of highly sensitive, magneto-optically tunable optical sensors, highlighting their potential in chemical detection and medical diagnostics.</p>","PeriodicalId":48608,"journal":{"name":"Biosensors-Basel","volume":"15 9","pages":""},"PeriodicalIF":5.6000,"publicationDate":"2025-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12467783/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biosensors-Basel","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.3390/bios15090630","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
This study presents a theoretical investigation of a terahertz (THz) surface plasmon resonance (SPR) optical biosensor utilizing a graphene-integrated Otto configuration. Through systematic numerical simulations, we demonstrate that actively modulating graphene's conductivity via an external magnetic field enables tunable SPR behavior with high phase sensitivity. The proposed sensor achieves a phase sensitivity of up to 3.1043×105 deg RIU-1 in liquid sensing and 2.5854×104 deg RIU-1 in gas sensing. This simulation-based work establishes a foundational framework for the development of highly sensitive, magneto-optically tunable optical sensors, highlighting their potential in chemical detection and medical diagnostics.
Biosensors-BaselBiochemistry, Genetics and Molecular Biology-Clinical Biochemistry
CiteScore
6.60
自引率
14.80%
发文量
983
审稿时长
11 weeks
期刊介绍：
Biosensors (ISSN 2079-6374) provides an advanced forum for studies related to the science and technology of biosensors and biosensing. It publishes original research papers, comprehensive reviews and communications. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Electronic files and software regarding the full details of the calculation or experimental procedure, if unable to be published in a normal way, can be deposited as supplementary electronic material.
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