Adequate Levels of Vitamin D Are Protective of Executive Functions in Patients with Chronic Mental Health.

IF 0.8 4区 心理学 Q3 PSYCHOLOGY, MULTIDISCIPLINARY
International Journal of Psychological Research Pub Date : 2025-07-25 eCollection Date: 2025-01-01 DOI:10.21500/20112084.7279
José Alejandro Valdevila-Figueira, Bryan Jauregui-Ruiz, Sergio Esteban Castillo-Jaramillo, Indira Dayana Carvajal-Parra, Rocío Valdevila-Santiesteban, Luis Patricio Benenaula-Vargas
{"title":"Adequate Levels of Vitamin D Are Protective of Executive Functions in Patients with Chronic Mental Health.","authors":"José Alejandro Valdevila-Figueira, Bryan Jauregui-Ruiz, Sergio Esteban Castillo-Jaramillo, Indira Dayana Carvajal-Parra, Rocío Valdevila-Santiesteban, Luis Patricio Benenaula-Vargas","doi":"10.21500/20112084.7279","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Vitamin D is a neurosteroid that modulates multiple brain functions and may be involved in the clinical presentation of psychotic disorders. Vitamin D deficiency has been associated with schizophrenia and cognitive decline, particularly in executive functions.</p><p><strong>Objective: </strong>To evaluate the relationship between vitamin D levels and performance in executive functions, processing speed, accuracy, and concentration in patients with schizophrenia and other organic mental disorders.</p><p><strong>Method: </strong>Retrospective, cross-sectional study with convenience sampling. The sample consisted of 113 adults (66 with schizophrenia and 47 with other organic mental conditions) admitted to the Institute of Neurosciences of Guayaquil, aged between 22 and 85 years.</p><p><strong>Results: </strong>The findings indicate a significant correlation between vitamin D levels and executive function performance. Higher levels of vitamin D were associated with less decline in executive functions in patients with schizophrenia and organ damage. Processing speed was higher in patients with optimal vitamin D levels compared to those with deficiency. In patients with organ damage, low vitamin D levels were associated with lower accuracy and concentration.</p><p><strong>Conclusions: </strong>This study suggests that adequate vitamin D levels may help preserve executive functions in people with schizophrenia and other organic mental disorders. Vitamin D supplementation is recommended in treatments to improve clinical outcomes and quality of life for these patients. Early detection and intervention are crucial to prevent further cognitive decline.</p>","PeriodicalId":46542,"journal":{"name":"International Journal of Psychological Research","volume":"18 1","pages":"106-114"},"PeriodicalIF":0.8000,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12410227/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Psychological Research","FirstCategoryId":"102","ListUrlMain":"https://doi.org/10.21500/20112084.7279","RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"PSYCHOLOGY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0

Abstract

Introduction: Vitamin D is a neurosteroid that modulates multiple brain functions and may be involved in the clinical presentation of psychotic disorders. Vitamin D deficiency has been associated with schizophrenia and cognitive decline, particularly in executive functions.

Objective: To evaluate the relationship between vitamin D levels and performance in executive functions, processing speed, accuracy, and concentration in patients with schizophrenia and other organic mental disorders.

Method: Retrospective, cross-sectional study with convenience sampling. The sample consisted of 113 adults (66 with schizophrenia and 47 with other organic mental conditions) admitted to the Institute of Neurosciences of Guayaquil, aged between 22 and 85 years.

Results: The findings indicate a significant correlation between vitamin D levels and executive function performance. Higher levels of vitamin D were associated with less decline in executive functions in patients with schizophrenia and organ damage. Processing speed was higher in patients with optimal vitamin D levels compared to those with deficiency. In patients with organ damage, low vitamin D levels were associated with lower accuracy and concentration.

Conclusions: This study suggests that adequate vitamin D levels may help preserve executive functions in people with schizophrenia and other organic mental disorders. Vitamin D supplementation is recommended in treatments to improve clinical outcomes and quality of life for these patients. Early detection and intervention are crucial to prevent further cognitive decline.

充足的维生素D水平对慢性精神疾病患者的执行功能有保护作用。
简介:维生素D是一种调节多种脑功能的神经类固醇,可能与精神障碍的临床表现有关。维生素D缺乏与精神分裂症和认知能力下降有关,尤其是在执行功能方面。目的:探讨维生素D水平与精神分裂症及其他器质性精神障碍患者执行功能、处理速度、准确性和注意力的关系。方法:采用方便抽样的回顾性横断面研究。样本包括113名成年人(66名患有精神分裂症,47名患有其他有机精神疾病),他们被瓜亚基尔神经科学研究所录取,年龄在22岁到85岁之间。结果:研究结果表明,维生素D水平与执行功能表现之间存在显著相关性。高水平的维生素D与精神分裂症和器官损伤患者的执行功能下降程度较低有关。与缺乏维生素D的患者相比,维生素D水平最佳的患者处理速度更快。在器官受损的患者中,低维生素D水平与较低的准确性和浓度相关。结论:这项研究表明,足够的维生素D水平可能有助于保持精神分裂症和其他器质性精神障碍患者的执行功能。建议在治疗中补充维生素D,以改善这些患者的临床结果和生活质量。早期发现和干预对于防止认知能力进一步下降至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
International Journal of Psychological Research
International Journal of Psychological Research PSYCHOLOGY, MULTIDISCIPLINARY-
CiteScore
2.30
自引率
9.10%
发文量
22
审稿时长
16 weeks
期刊介绍: The International Journal of Psychological Research (Int.j.psychol.res) is the Faculty of Psychology’s official publication of San Buenaventura University in Medellin, Colombia. Int.j.psychol.res relies on a vast and diverse theoretical and thematic publishing material, which includes unpublished productions of diverse psychological issues and behavioral human areas such as psychiatry, neurosciences, mental health, among others.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信