Sarah N Bosch, Peres Badial, Heather A Roe, Tomer Shua-Haim, Oscar Alas, Hayley Paradise, Airtor Gallastegui, Diego De Gasperi, Ian K Hawkins, Aline Rodrigues Hoffmann, Christopher J Lanier, Tara P Arndt
{"title":"Cryptococcus gattii Infection in the Carpal Joint of a Goat.","authors":"Sarah N Bosch, Peres Badial, Heather A Roe, Tomer Shua-Haim, Oscar Alas, Hayley Paradise, Airtor Gallastegui, Diego De Gasperi, Ian K Hawkins, Aline Rodrigues Hoffmann, Christopher J Lanier, Tara P Arndt","doi":"10.1111/vcp.70048","DOIUrl":null,"url":null,"abstract":"<p><p>A 5-year-old LaMancha goat buck presented for evaluation of a 1-week history of progressive lameness and carpal swelling in the left thoracic limb. Cytology performed on an aspirate from the left radiocarpal joint identified abundant round to oval, thickly encapsulated, extracellular yeast organisms that occasionally exhibited narrow-based budding, features compatible with Cryptococcus spp. yeast. The patient was euthanized due to poor prognosis, and a necropsy was performed. Histopathology confirmed the presence of numerous fungal yeast associated with the left radiocarpal joint. A cryptococcal serum latex agglutination test was negative. However, panfungal PCR and fungal culture identified the organisms as Cryptococcus gattii. This report describes, for the first time, a case of a C. gattii infection affecting the joint of a goat.</p>","PeriodicalId":23593,"journal":{"name":"Veterinary clinical pathology","volume":" ","pages":""},"PeriodicalIF":1.1000,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Veterinary clinical pathology","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1111/vcp.70048","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
A 5-year-old LaMancha goat buck presented for evaluation of a 1-week history of progressive lameness and carpal swelling in the left thoracic limb. Cytology performed on an aspirate from the left radiocarpal joint identified abundant round to oval, thickly encapsulated, extracellular yeast organisms that occasionally exhibited narrow-based budding, features compatible with Cryptococcus spp. yeast. The patient was euthanized due to poor prognosis, and a necropsy was performed. Histopathology confirmed the presence of numerous fungal yeast associated with the left radiocarpal joint. A cryptococcal serum latex agglutination test was negative. However, panfungal PCR and fungal culture identified the organisms as Cryptococcus gattii. This report describes, for the first time, a case of a C. gattii infection affecting the joint of a goat.
期刊介绍:
Veterinary Clinical Pathology is the official journal of the American Society for Veterinary Clinical Pathology (ASVCP) and the European Society of Veterinary Clinical Pathology (ESVCP). The journal''s mission is to provide an international forum for communication and discussion of scientific investigations and new developments that advance the art and science of laboratory diagnosis in animals. Veterinary Clinical Pathology welcomes original experimental research and clinical contributions involving domestic, laboratory, avian, and wildlife species in the areas of hematology, hemostasis, immunopathology, clinical chemistry, cytopathology, surgical pathology, toxicology, endocrinology, laboratory and analytical techniques, instrumentation, quality assurance, and clinical pathology education.