High-energy-density acoustofluidic device using a double-parabolic ultrasonic transducer.

IF 4.4 2区 物理与天体物理 Q2 PHYSICS, APPLIED
Enrico Corato, Ola Jakobsson, Wei Qiu, Takeshi Morita, Per Augustsson
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Abstract

High-acoustic-energy-density acoustofluidic devices are necessary to make this technology a viable option for clinical applications in the biomedical field. We present a mechanical interface that enables delivery of a high-amplitude acoustic field inside a fluid cavity by translating the vibrations from two large piezoelectric elements into a microfluidic chip. The study comprises both experimental characterization of a double-parabolic metallic acoustic waveguide and simulations of its working mechanism in two dimensions. We could focus 4.9-μm polystyrene particles at a flowrate of 5 ml/min, corresponding to an average retention time of 13.5 ms for particles in the actuated area. Moreover, we measured the acoustic energy density in the channel at stopped-flow condition, obtaining an average value of 1207 J/m3 and a maximum value of 2977 J/m3 with an input electrical power of 1.5 W. By comparing the simulation results with laser-Doppler vibrometer measurements, we confirmed that transverse sound waves play a significant role in the working mechanism of the double-parabolic structure, thus paving the way for further future optimization of the waveguide design.

采用双抛物型超声换能器的高能量密度声流装置。
为了使该技术在生物医学领域的临床应用成为可行的选择,高声能密度的声流装置是必要的。我们提出了一种机械界面,通过将两个大型压电元件的振动转化为微流控芯片,可以在流体腔内传递高振幅声场。本研究包括双抛物型金属声波导的实验表征和其工作机理的二维模拟。我们可以在5 ml/min的流速下聚焦4.9 μm的聚苯乙烯颗粒,对应于驱动区域颗粒的平均停留时间为13.5 ms。此外,我们测量了在停流条件下通道内的声能密度,在输入功率为1.5 W时,声能密度平均值为1207 J/m3,最大值为2977 J/m3。通过将仿真结果与激光多普勒测振仪的测量结果进行比较,我们证实了横向声波在双抛物结构的工作机制中发挥了重要作用,从而为进一步优化波导设计奠定了基础。
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来源期刊
Physical Review Applied
Physical Review Applied PHYSICS, APPLIED-
CiteScore
7.80
自引率
8.70%
发文量
760
审稿时长
2.5 months
期刊介绍: Physical Review Applied (PRApplied) publishes high-quality papers that bridge the gap between engineering and physics, and between current and future technologies. PRApplied welcomes papers from both the engineering and physics communities, in academia and industry. PRApplied focuses on topics including: Biophysics, bioelectronics, and biomedical engineering, Device physics, Electronics, Technology to harvest, store, and transmit energy, focusing on renewable energy technologies, Geophysics and space science, Industrial physics, Magnetism and spintronics, Metamaterials, Microfluidics, Nonlinear dynamics and pattern formation in natural or manufactured systems, Nanoscience and nanotechnology, Optics, optoelectronics, photonics, and photonic devices, Quantum information processing, both algorithms and hardware, Soft matter physics, including granular and complex fluids and active matter.
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