[Prosthetic Heart Valves:Recent Advances and Future Perspectives].

Q4 Medicine
Tomonari Fujimori, Atsushi Yamaguchi
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引用次数: 0

Abstract

Recent years have witnessed significant advancements in prosthetic heart valves, particularly bioprosthetic valves. The main challenges for bioprosthetic valves have been structural valve deterioration (SVD) and long-term durability. This review focuses on three major innovations: anti-calcification treatments, valve-in-valve (ViV) compatible designs, and sutureless/rapid deployment valves. Modern bioprosthetic valves incorporate proprietary anti-calcification technologies that have demonstrated excellent mid-term durability in clinical trials. Valve designs increasingly consider future ViV procedures, incorporating features such as expandable bands, optimized dimensions, and enhanced radiopaque markers. Sutureless/rapid deployment valves have shown promising results with reduced operative times, particularly beneficial for minimally invasive approaches. Recent guidelines reflect these advances, with age thresholds for bioprosthetic valves decreasing. Emerging evidence suggests tissue-specific characteristics may influence valve selection. Future developments will likely focus on further enhancing durability and establishing personalized valve selection algorithms.

[人工心脏瓣膜:最新进展和未来展望]
近年来,人工心脏瓣膜,特别是生物人工心脏瓣膜取得了重大进展。生物假体瓣膜面临的主要挑战是瓣膜结构恶化(SVD)和长期耐用性。本文综述了三个主要的创新:抗钙化处理、阀中阀(ViV)兼容设计和无缝合线/快速部署阀。现代生物假体瓣膜采用专有的抗钙化技术,在临床试验中表现出优异的中期耐久性。阀门设计越来越多地考虑未来的ViV程序,包括可扩展的波段、优化的尺寸和增强的不透射线标记等特征。无缝线/快速部署瓣膜在减少手术时间,特别是微创入路方面显示出良好的效果。最近的指南反映了这些进展,生物假体瓣膜的年龄门槛降低了。新出现的证据表明,组织特异性特征可能会影响瓣膜的选择。未来的发展可能集中在进一步提高耐久性和建立个性化的阀门选择算法上。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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