Original Locking Rod System Designed for Diaphyseal Fractures of Long Bones.

IF 5.2 3区医学 Q1 ENGINEERING, BIOMEDICAL

Journal of Functional Biomaterials Pub Date : 2025-09-15 DOI:10.3390/jfb16090348

Liviu-Coriolan Misca, Cristian Constantin Croicu, Adrian Emil Lazarescu, Mihai-Alexandru Sandesc, Jenel Marian Patrascu, Sorin Florescu, Jenel Marian Patrascu

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引用次数: 0

Abstract

Introduction: Intramedullary nailing is widely used for long bone fractures. Traditional systems are reliable, but they present some complications regarding lack of modularity or possible growth plate damage. Methods: A novel locking rod-screw system featuring a central rod and a grooved screw with a secondary interlocking mechanism was developed and tested. Mechanical testing followed ASTM F543 and ISO 6475 standards using a 3.0 mm steel alloy prototype. Results: The system withstood mechanical testing >200,000 cycles at loads up to 200 N with no rates of failure or loosening, significantly outperforming other implants of the same size (3.0 mm TENS). Conclusions: The proposed implant demonstrates superior biomechanical performance in vitro, enabled by its unique hollow screw and secondary locking configuration. This modular and minimally invasive system shows promise for use in cases of smaller long bones, personalized paediatric fractures, and all types of diaphyseal fractures, but does warrant in vivo validation.

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专为长骨骨干骨折设计的独创锁定棒系统。

髓内钉广泛应用于长骨骨折。传统的系统是可靠的，但它们存在一些复杂性，如缺乏模块化或可能的生长板损坏。方法：开发并试验了一种新型的锁紧杆-螺钉系统，该系统具有中心杆和凹槽螺钉，具有二级联锁机构。机械测试遵循ASTM F543和ISO 6475标准，使用3.0毫米钢合金原型。结果：该系统在高达200 N的载荷下承受了20万次的机械测试，无失败率或松动率，明显优于其他相同尺寸的种植体（3.0 mm TENS）。结论：该种植体具有独特的空心螺钉和二次锁定结构，具有优异的体外生物力学性能。这种模块化的微创系统有望用于较小的长骨、个性化的儿科骨折和所有类型的骨干骨折，但仍需在体内验证。

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来源期刊

Journal of Functional Biomaterials Engineering-Biomedical Engineering

CiteScore

4.60

自引率

4.20%

发文量

226

审稿时长

11 weeks

期刊介绍： Journal of Functional Biomaterials (JFB, ISSN 2079-4983) is an international and interdisciplinary scientific journal that publishes regular research papers (articles), reviews and short communications about applications of materials for biomedical use. JFB covers subjects from chemistry, pharmacy, biology, physics over to engineering. The journal focuses on the preparation, performance and use of functional biomaterials in biomedical devices and their behaviour in physiological environments. Our aim is to encourage scientists to publish their results in as much detail as possible. Therefore, there is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Several topical special issues will be published. Scope: adhesion, adsorption, biocompatibility, biohybrid materials, bio-inert materials, biomaterials, biomedical devices, biomimetic materials, bone repair, cardiovascular devices, ceramics, composite materials, dental implants, dental materials, drug delivery systems, functional biopolymers, glasses, hyper branched polymers, molecularly imprinted polymers (MIPs), nanomedicine, nanoparticles, nanotechnology, natural materials, self-assembly smart materials, stimuli responsive materials, surface modification, tissue devices, tissue engineering, tissue-derived materials, urological devices.