Environmental factors are responsible for the rise of atopic dermatitis in dogs: veterinarians should focus on modifiable influences.

IF 1.8 2区 农林科学 Q2 VETERINARY SCIENCES
Rosanna Marsella
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Abstract

Over the past few decades, living conditions for people and dogs have changed significantly, along with a rise in allergy rates in both species. Since dogs share living spaces with humans and are subject to modern urban living, dogs now face increased exposure to pollution and less contact with farm animals and rural environments. Rural living promotes exposure to a diverse microbiota, which shapes the immune response. Pollution has many detrimental effects, ranging from epithelial damage to epigenetic changes. Pollutants disrupt epithelia, promoting low-grade chronic inflammation, dysbiosis, increased allergen penetration, and sensitization. Dogs today face higher exposure to air pollutants, chemicals, plastics, and surfactants, whether from detergents, topical products, or additives in commercial foods. While in the past dogs were fed a variety of home-cooked diets, table scraps, and raw meats, they are now more likely to be fed commercial diets regularly. Dogs today lead more sedentary lives, with increased obesity and reduced exercise, factors that are known to raise the risk of developing atopic dermatitis in humans. Many owners experience higher stress levels, and dogs tend to mirror their owners' stress and anxiety. The effects of environmental and dietary factors on canine atopic dermatitis are discussed, emphasizing the current evidence from published epidemiological studies. While some studies report associations, others identify early-life factors that can influence disease development. The companion Currents in One Health article by Marsella, AJVR, January 2026, addresses the theories proposed to explain these associations and provides pathogenetic mechanisms for the rise of allergic diseases in people and dogs.

环境因素是狗的特应性皮炎上升的原因:兽医应该关注可改变的影响。
在过去的几十年里,人和狗的生活条件发生了显著变化,两种动物的过敏率都有所上升。由于狗与人类共享生活空间,并受到现代城市生活的影响,狗现在面临着越来越多的污染,与农场动物和农村环境的接触越来越少。农村生活促进接触多样化的微生物群,从而形成免疫反应。污染有许多有害影响,从上皮损伤到表观遗传变化。污染物破坏上皮,促进低级别慢性炎症,生态失调,增加过敏原渗透和致敏。今天的狗面临着更多的空气污染物、化学物质、塑料和表面活性剂,无论是来自洗涤剂、局部产品还是商业食品中的添加剂。过去,人们给狗喂食各种家常菜、剩饭剩饭和生肉,而现在,人们更有可能定期给它们喂食商业饲料。如今,狗狗的生活更久坐不动,肥胖增加,运动减少,这些因素已知会增加人类患特应性皮炎的风险。许多主人承受着更大的压力,而狗往往会反映主人的压力和焦虑。本文讨论了环境和饮食因素对犬特应性皮炎的影响,强调了已发表的流行病学研究的最新证据。虽然一些研究报告了两者之间的关联,但另一些研究则确定了可能影响疾病发展的早期因素。Marsella于2026年1月在《AJVR》上发表了一篇题为《同一健康中的电流》的文章,阐述了解释这些关联的理论,并提供了人类和狗中过敏性疾病增加的发病机制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.60
自引率
15.80%
发文量
539
审稿时长
6-16 weeks
期刊介绍: Published twice monthly, this peer-reviewed, general scientific journal provides reports of clinical research, feature articles and regular columns of interest to veterinarians in private and public practice. The News and Classified Ad sections are posted online 10 days to two weeks before they are delivered in print.
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