[Expression of Concern] Podoplanin‑mediated TGF‑β‑induced epithelial-mesen-chymal transition and its correlation with bHLH transcription factor DEC in TE‑11 cells.

IF 4.9 3区 医学 Q1 ONCOLOGY
International journal of oncology Pub Date : 2025-12-01 Epub Date: 2025-09-26 DOI:10.3892/ijo.2025.5805
Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
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引用次数: 0

Abstract

Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that, for the scratch‑wound assay experiments shown in Fig. 6 on p. 2318, the 'control siRNA/24 h' and 'podoplanin siRNA/48 h' panels contained an overlapping section of data; such that these data, which were intended to show the results from differently performed experiments, appeared to have been derived from the same original source. Upon analyzing the data independently in the Editorial Office, it came to light that, in addition to control blots, the podoplanin blots were duplicated in Fig. 2A and B, and also in Fig. 3A and B, although it wasn't clear whether this was simply the way in which the authors had chosen to arrange the data in these figures, as the reported experimental conditions were the same in the respective figure parts. The authors were contacted by the Editorial Office to offer an explanation for these possible anomalies in the presentation of the data in this paper, although up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office conitnues to investigate this matter further. [International Journal of Oncology 48: 2310‑2320, 2016; DOI: 10.3892/ijo.2016.3445].

[表达关注]Podoplanin介导的TGF - β诱导的TE - 11细胞上皮-间质转化及其与bHLH转录因子DEC的相关性。
在上述论文发表后,一位关心的读者提请编辑注意,在2318页图6所示的划痕实验中,“对照siRNA/24 h”和“podoplanin siRNA/48 h”面板包含重叠的数据部分;因此,这些旨在显示不同实验结果的数据似乎来自同一个原始来源。在编辑部独立分析数据后发现,图2A和B中除了对照印迹外,podoplanin印迹也在图3A和B中重复,但不清楚这是否仅仅是作者选择在这些图中排列数据的方式,因为各自图部分报道的实验条件是相同的。编辑部联系了作者,要求他们解释本文中数据呈现中可能出现的异常,尽管到目前为止,他们还没有任何回应。由于编辑部已经意识到围绕本文科学完整性的潜在问题,在编辑部继续进一步调查此事的同时,我们发出一份关注表达,通知读者这一潜在问题。国际肿瘤学杂志48:2310‑2320,2016;DOI: 10.3892 / ijo.2016.3445]。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
9.60
自引率
0.00%
发文量
157
审稿时长
2.1 months
期刊介绍: The main aim of Spandidos Publications is to facilitate scientific communication in a clear, concise and objective manner, while striving to provide prompt publication of original works of high quality. The journals largely concentrate on molecular and experimental medicine, oncology, clinical and experimental cancer treatment and biomedical research. All journals published by Spandidos Publications Ltd. maintain the highest standards of quality, and the members of their Editorial Boards are world-renowned scientists.
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