Case Report: MRSA sepsis after pediatric traumatic pseudoaneurysm.

IF 2 3区 医学 Q2 PEDIATRICS
Frontiers in Pediatrics Pub Date : 2025-09-10 eCollection Date: 2025-01-01 DOI:10.3389/fped.2025.1648541
Xiongfeng Zhang, Hua Zhao, Qingtian Yang
{"title":"Case Report: MRSA sepsis after pediatric traumatic pseudoaneurysm.","authors":"Xiongfeng Zhang, Hua Zhao, Qingtian Yang","doi":"10.3389/fped.2025.1648541","DOIUrl":null,"url":null,"abstract":"<p><p>Pediatric vascular injuries are rare and present unique clinical challenges due to differences in vessel size, injury patterns, and long-term outcomes compared with adults. We report the case of an 11-year-old boy who developed a ruptured and infected superficial femoral artery pseudoaneurysm following closed blunt trauma, which was further complicated by sepsis and necrotizing fasciitis. The patient underwent urgent surgical repair with autologous great saphenous vein patch angioplasty, combined with extensive debridement of necrotic tissue. Postoperatively, methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) was identified, necessitating individualized, pharmacokinetically guided vancomycin therapy. This case highlights the importance of early vascular assessment following pediatric blunt trauma, the feasibility of autologous tissue reconstruction in infected arterial injuries, and the critical role of real-time therapeutic drug monitoring in optimizing the management of severe pediatric MRSA infections. This case underscores the need for multidisciplinary coordination and long-term follow-up to optimize outcomes in rare pediatric vascular trauma.</p>","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1648541"},"PeriodicalIF":2.0000,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12457290/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Pediatrics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3389/fped.2025.1648541","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0

Abstract

Pediatric vascular injuries are rare and present unique clinical challenges due to differences in vessel size, injury patterns, and long-term outcomes compared with adults. We report the case of an 11-year-old boy who developed a ruptured and infected superficial femoral artery pseudoaneurysm following closed blunt trauma, which was further complicated by sepsis and necrotizing fasciitis. The patient underwent urgent surgical repair with autologous great saphenous vein patch angioplasty, combined with extensive debridement of necrotic tissue. Postoperatively, methicillin-resistant Staphylococcus aureus (MRSA) was identified, necessitating individualized, pharmacokinetically guided vancomycin therapy. This case highlights the importance of early vascular assessment following pediatric blunt trauma, the feasibility of autologous tissue reconstruction in infected arterial injuries, and the critical role of real-time therapeutic drug monitoring in optimizing the management of severe pediatric MRSA infections. This case underscores the need for multidisciplinary coordination and long-term follow-up to optimize outcomes in rare pediatric vascular trauma.

Abstract Image

Abstract Image

病例报告:小儿创伤性假性动脉瘤后MRSA脓毒症。
与成人相比,儿童血管损伤是罕见的,并且由于血管大小、损伤模式和长期结果的差异而呈现出独特的临床挑战。我们报告一例11岁的男孩在闭合性钝性创伤后发生破裂和感染的股浅动脉假性动脉瘤,并进一步并发脓毒症和坏死性筋膜炎。患者接受了自体大隐静脉补片血管成形术的紧急手术修复,并对坏死组织进行了广泛的清创。术后发现耐甲氧西林金黄色葡萄球菌(MRSA),需要个体化、药代动力学指导的万古霉素治疗。该病例强调了儿童钝性创伤后早期血管评估的重要性,感染动脉损伤的自体组织重建的可行性,以及实时治疗药物监测在优化儿童严重MRSA感染管理中的关键作用。本病例强调需要多学科协调和长期随访,以优化罕见儿科血管创伤的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Frontiers in Pediatrics
Frontiers in Pediatrics Medicine-Pediatrics, Perinatology and Child Health
CiteScore
3.60
自引率
7.70%
发文量
2132
审稿时长
14 weeks
期刊介绍: Frontiers in Pediatrics (Impact Factor 2.33) publishes rigorously peer-reviewed research broadly across the field, from basic to clinical research that meets ongoing challenges in pediatric patient care and child health. Field Chief Editors Arjan Te Pas at Leiden University and Michael L. Moritz at the Children''s Hospital of Pittsburgh are supported by an outstanding Editorial Board of international experts. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. Frontiers in Pediatrics also features Research Topics, Frontiers special theme-focused issues managed by Guest Associate Editors, addressing important areas in pediatrics. In this fashion, Frontiers serves as an outlet to publish the broadest aspects of pediatrics in both basic and clinical research, including high-quality reviews, case reports, editorials and commentaries related to all aspects of pediatrics.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信