{"title":"Case Report: MRSA sepsis after pediatric traumatic pseudoaneurysm.","authors":"Xiongfeng Zhang, Hua Zhao, Qingtian Yang","doi":"10.3389/fped.2025.1648541","DOIUrl":null,"url":null,"abstract":"<p><p>Pediatric vascular injuries are rare and present unique clinical challenges due to differences in vessel size, injury patterns, and long-term outcomes compared with adults. We report the case of an 11-year-old boy who developed a ruptured and infected superficial femoral artery pseudoaneurysm following closed blunt trauma, which was further complicated by sepsis and necrotizing fasciitis. The patient underwent urgent surgical repair with autologous great saphenous vein patch angioplasty, combined with extensive debridement of necrotic tissue. Postoperatively, methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) was identified, necessitating individualized, pharmacokinetically guided vancomycin therapy. This case highlights the importance of early vascular assessment following pediatric blunt trauma, the feasibility of autologous tissue reconstruction in infected arterial injuries, and the critical role of real-time therapeutic drug monitoring in optimizing the management of severe pediatric MRSA infections. This case underscores the need for multidisciplinary coordination and long-term follow-up to optimize outcomes in rare pediatric vascular trauma.</p>","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1648541"},"PeriodicalIF":2.0000,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12457290/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Pediatrics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3389/fped.2025.1648541","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0
Abstract
Pediatric vascular injuries are rare and present unique clinical challenges due to differences in vessel size, injury patterns, and long-term outcomes compared with adults. We report the case of an 11-year-old boy who developed a ruptured and infected superficial femoral artery pseudoaneurysm following closed blunt trauma, which was further complicated by sepsis and necrotizing fasciitis. The patient underwent urgent surgical repair with autologous great saphenous vein patch angioplasty, combined with extensive debridement of necrotic tissue. Postoperatively, methicillin-resistant Staphylococcus aureus (MRSA) was identified, necessitating individualized, pharmacokinetically guided vancomycin therapy. This case highlights the importance of early vascular assessment following pediatric blunt trauma, the feasibility of autologous tissue reconstruction in infected arterial injuries, and the critical role of real-time therapeutic drug monitoring in optimizing the management of severe pediatric MRSA infections. This case underscores the need for multidisciplinary coordination and long-term follow-up to optimize outcomes in rare pediatric vascular trauma.
期刊介绍:
Frontiers in Pediatrics (Impact Factor 2.33) publishes rigorously peer-reviewed research broadly across the field, from basic to clinical research that meets ongoing challenges in pediatric patient care and child health. Field Chief Editors Arjan Te Pas at Leiden University and Michael L. Moritz at the Children''s Hospital of Pittsburgh are supported by an outstanding Editorial Board of international experts. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.
Frontiers in Pediatrics also features Research Topics, Frontiers special theme-focused issues managed by Guest Associate Editors, addressing important areas in pediatrics. In this fashion, Frontiers serves as an outlet to publish the broadest aspects of pediatrics in both basic and clinical research, including high-quality reviews, case reports, editorials and commentaries related to all aspects of pediatrics.