The global burden of adolescent acne: trends from 1990 to 2021 and future projections to 2050.

IF 2.7 3区医学 Q2 DERMATOLOGY

Dermatology Pub Date : 2025-09-25 DOI:10.1159/000548450

Gang Li, Xuezhuang Yue, Yan Lu, Chengzhong Zhang

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引用次数: 0

Abstract

Introduction Adolescent acne poses unique therapeutic challenges and imposes a substantial burden. However, study of its global impact has been limited and neglected. Objective To analyze the global disease burden and epidemiologic trend of adolescent acne. Methods Data was extracted from the global burden of disease Study the 2021 database. All the analysis procedures graphic representation were undertaken by R statistical software and GraphPad Prism 9. Results The global burden of adolescent acne increased significantly from 1990 to 2021, with consistently higher rates observed in females compared to males. Meanwhile, both the age-standardized incidence rate (ASIR), age-standardized prevalence rate (ASPR) and age-standardized YLD rate (ASDR) continued to rise significantly, with an average annual percentage change (AAPC) of 0.7%, 0.6%, 0.6%. Population analysis revealed a unimodal age distribution, characterized by high burden among adolescent with the age of 11-14. National and Regional, the distribution of the disease burden was highly uneven. The global burden can be mostly attributed to epidemiological changes (58.7%), aging (40.0%). Significant regional disparities grouped by socio-demographic index (SDI) were observed. Projections indicate that by 2050, the incidence, ASIR, prevalence, ASPR, DALYs and ASDR of of adolescent acne will rise to 122 million, 4,265 per 100,000, 201 million, 7,015 per 100,000, 4.326 million and 151.2 per 100,000. Conclusion The study demonstrates a significant and growing global burden of adolescent acne from 1990 to 2021, underscoring the urgent need for targeted prevention and management strategies worldwide.

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青少年痤疮的全球负担：1990年至2021年的趋势和到2050年的未来预测。

青少年痤疮提出了独特的治疗挑战，并施加了实质性的负担。然而，对其全球影响的研究一直受到限制和忽视。目的分析全球青少年痤疮的疾病负担及流行趋势。方法从2021年全球疾病负担研究数据库中提取数据。所有分析过程的图形表示均由R统计软件和GraphPad Prism 9完成。结果从1990年到2021年，全球青少年痤疮负担显著增加，女性的比例始终高于男性。同时，年龄标准化发病率（ASIR）、年龄标准化患病率（ASPR）和年龄标准化YLD率（ASDR）继续显著上升，年均百分比变化（AAPC）分别为0.7%、0.6%、0.6%。人口分析显示年龄分布呈单峰分布，11-14岁青少年负担高。在国家和区域，疾病负担的分布极不平衡。全球负担主要归因于流行病学变化（58.7%）和老龄化（40.0%）。按社会人口指数（SDI）分组，观察到显著的区域差异。预计到2050年，青少年痤疮的发病率、ASIR、患病率、ASPR、DALYs和ASDR将分别上升至1.22亿、4265 / 10万、2.01亿、7015 / 10万、432.6万和151.2 / 10万。该研究表明，从1990年到2021年，全球青少年痤疮负担显著增加，强调迫切需要在全球范围内制定有针对性的预防和管理策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Dermatology 医学-皮肤病学

CiteScore

6.40

自引率

2.90%

发文量

审稿时长

1 months

期刊介绍： Published since 1893, ''Dermatology'' provides a worldwide survey of clinical and investigative dermatology. Original papers report clinical and laboratory findings. In order to inform readers of the implications of recent research, editorials and reviews prepared by invited, internationally recognized scientists are regularly featured. In addition to original papers, the journal publishes rapid communications, short communications, and letters to ''Dermatology''. ''Dermatology'' answers the complete information needs of practitioners concerned with progress in research related to skin, clinical dermatology and therapy. The journal enjoys a high scientific reputation with a continually increasing impact factor and an equally high circulation.