Gait phase recognition of children with cerebral palsy via deep learning based on IMU data from a soft ankle exoskeleton.

IF 4.8 3区 工程技术 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Frontiers in Bioengineering and Biotechnology Pub Date : 2025-09-10 eCollection Date: 2025-01-01 DOI:10.3389/fbioe.2025.1679812
Zhi Pang, Zewei Li, Ying Li, Bingshan Hu, Qiu Wang, Hongliu Yu, Wujing Cao
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Abstract

Accurate gait-phase identification in children with Cerebral Palsy (CP) constitutes a pivotal prerequisite for evidence-based rehabilitation. Addressing the precise detection of gait disturbances under natural ambulation, we propose a deep-learning framework that integrates a stacked denoising autoencoder (SDA) with a long short-term memory network (SDA-LSTM) to classify four canonical gait phases. A community-oriented dataset was constructed by synchronizing ankle-mounted inertial measurement units (IMU) with plantar-pressure insoles; natural gait sequences of six children with mild CP were acquired in open environments. The SDA layer robustly extracts discriminative representations from non-stationary, high-noise signals, whereas the LSTM module models inter-phase temporal dependencies, thereby enhancing generalization cross-user. In noise-free conditions the SDA-LSTM framework attained 97.83% accuracy, significantly exceeding SVM (94.68%), random forest (96.05%), and standalone LSTM (95.86%). Under additive Gaussian noise with SNR ranging from 5 to 30 dB, the model preserved stable performance; at 10 dB SNR (Signal-to-Noise Ratio), accuracy remained 90.96%, corroborating its exceptional robustness. These findings demonstrate that SDA-LSTM effectively handles the complex, heterogeneous gait patterns of children with CP and is readily deployable for clinical assessment and exoskeletal assistance systems, indicating substantial translational potential.

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基于软踝外骨骼IMU数据的深度学习脑性瘫痪儿童步态相位识别。
脑瘫(CP)儿童步态期的准确识别是循证康复的关键前提。为了精确检测自然行走下的步态干扰,我们提出了一种深度学习框架,该框架将堆叠去噪自编码器(SDA)与长短期记忆网络(SDA- lstm)相结合,对四个典型的步态阶段进行分类。通过同步踝关节惯性测量单元(IMU)与足底压力鞋垫,构建面向社区的数据集;在开放环境下获得6例轻度CP患儿的自然步态序列。SDA层鲁棒地从非平稳、高噪声信号中提取判别表示,而LSTM模块对相间时间依赖性进行建模,从而增强了跨用户的泛化能力。在无噪声条件下,SDA-LSTM框架的准确率达到97.83%,显著超过支持向量机(94.68%)、随机森林(96.05%)和独立LSTM(95.86%)。在信噪比为5 ~ 30 dB的加性高斯噪声下,模型保持稳定的性能;在信噪比为10 dB时,准确率保持在90.96%,证实了其出色的鲁棒性。这些研究结果表明,SDA-LSTM有效地处理了CP患儿复杂、异质性的步态模式,并且很容易用于临床评估和外骨骼辅助系统,表明了巨大的转化潜力。
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来源期刊
Frontiers in Bioengineering and Biotechnology
Frontiers in Bioengineering and Biotechnology Chemical Engineering-Bioengineering
CiteScore
8.30
自引率
5.30%
发文量
2270
审稿时长
12 weeks
期刊介绍: The translation of new discoveries in medicine to clinical routine has never been easy. During the second half of the last century, thanks to the progress in chemistry, biochemistry and pharmacology, we have seen the development and the application of a large number of drugs and devices aimed at the treatment of symptoms, blocking unwanted pathways and, in the case of infectious diseases, fighting the micro-organisms responsible. However, we are facing, today, a dramatic change in the therapeutic approach to pathologies and diseases. Indeed, the challenge of the present and the next decade is to fully restore the physiological status of the diseased organism and to completely regenerate tissue and organs when they are so seriously affected that treatments cannot be limited to the repression of symptoms or to the repair of damage. This is being made possible thanks to the major developments made in basic cell and molecular biology, including stem cell science, growth factor delivery, gene isolation and transfection, the advances in bioengineering and nanotechnology, including development of new biomaterials, biofabrication technologies and use of bioreactors, and the big improvements in diagnostic tools and imaging of cells, tissues and organs. In today`s world, an enhancement of communication between multidisciplinary experts, together with the promotion of joint projects and close collaborations among scientists, engineers, industry people, regulatory agencies and physicians are absolute requirements for the success of any attempt to develop and clinically apply a new biological therapy or an innovative device involving the collective use of biomaterials, cells and/or bioactive molecules. “Frontiers in Bioengineering and Biotechnology” aspires to be a forum for all people involved in the process by bridging the gap too often existing between a discovery in the basic sciences and its clinical application.
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