Secondary Perianal Paget's Disease Originating From Adenocarcinoma of the Anorectal Junction: A Case Report.

IF 2.2 4区医学 Q3 DERMATOLOGY

Clinical, Cosmetic and Investigational Dermatology Pub Date : 2025-09-20 eCollection Date: 2025-01-01 DOI:10.2147/CCID.S546040

Jun He, Rong-Chao He, Jian-Zhong Peng, Hou-Dong Wang, Tao Wang, Si-Jia Lu, Xiu-Feng Zhang, Zhong Shen

引用次数: 0

Abstract

Secondary extramammary Paget's disease (EMPD), originating from the cutaneous dissemination of malignant cells, represents a rare subtype prone to misdiagnosis. This study presents a case of secondary perianal Paget's disease (PPD) associated with adenocarcinoma at the anorectal junction. Preoperative full-thickness mapping biopsy was utilized for the assessment of lesion margins. The patient demonstrated favorable postoperative recovery following a multimodal therapeutic regimen.

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继发性肛周佩吉特病起源于肛肠交界处腺癌1例报告。

继发性乳腺外佩吉特病（EMPD），起源于恶性细胞的皮肤播散，是一种罕见的亚型，容易误诊。本研究报告一例继发性肛周佩吉特病（PPD）伴肛门直肠交界处腺癌。术前全层穿刺活检用于评估病变边缘。患者表现出良好的术后恢复多模式治疗方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical, Cosmetic and Investigational Dermatology Medicine-Dermatology

CiteScore

2.80

自引率

4.30%

发文量

353

审稿时长

16 weeks

期刊介绍： Clinical, Cosmetic and Investigational Dermatology is an international, peer-reviewed, open access journal that focuses on the latest clinical and experimental research in all aspects of skin disease and cosmetic interventions. Normal and pathological processes in skin development and aging, their modification and treatment, as well as basic research into histology of dermal and dermal structures that provide clinical insights and potential treatment options are key topics for the journal. Patient satisfaction, preference, quality of life, compliance, persistence and their role in developing new management options to optimize outcomes for target conditions constitute major areas of interest. The journal is characterized by the rapid reporting of clinical studies, reviews and original research in skin research and skin care. All areas of dermatology will be covered; contributions will be welcomed from all clinicians and basic science researchers globally.