Perioperative symptoms in patients with thyroid cancer: a cross-sectional and longitudinal network analysis.

IF 3.3 3区 医学 Q3 ENDOCRINOLOGY & METABOLISM
Yuyan Yin, Zilin Fang, Xin Sheng, Jiaqi Li, Juan Xu, Ting Wang
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引用次数: 0

Abstract

Background: Patients with thyroid cancer experience a range of symptoms during surgical treatment. Identifying their core symptoms and understanding their dynamic changes can help improve the efficiency of clinical symptom management.

Methods: A longitudinal observational study design was used, and convenience sampling method was applied to select thyroid cancer patients who attended the Department of Thyroid and Breast Surgery in a tertiary hospital in Suzhou City from October 2024 to April 2025. A general information questionnaire and the Chinese version of the Memory Symptom Assessment Scale were used to assess the patients 1 day before surgery (T1), 1-2 days after surgery (T2) and 2 weeks after surgery (T3). The symptom severity bias correlation network was constructed through R language, and the core symptoms of T1, T2 and T3 were identified.

Results: This study finally included 248 patients with thyroid cancer. The results showed that the three symptoms with the highest strength centrality in the T1 network were lack of appetite (rs=1.536), worrying (rs=1.442), and feeling nervous (rs=1.439). The three symptoms with the highest strength centrality in the T2 network were numbness/tingling in hands/feet (rs=1.613), lack of appetite (rs=1.433), and nausea (rs=1.294). The three symptoms with the highest strength centrality in the T3 network were difficulty swallowing (rs=1.778), feeling nervous (rs=1.681), and neck discomfort (rs=1.520). Neck discomfort (rs2=1.281, rs3=1.520) was the core symptom that was more stable postoperatively. In the test of network structural invariance, there were significant differences between T1 and T2 (M=0.78, P<0.001), T1 and T3 (M=0.45, P=0.009), and T2 and T3 (M=0.66, P<0.001). In terms of overall network connectivity strength, there were significant differences between T1 (GS=6.86) and T3 (GS=4.12), T2 (GS=7.66) and T3 (P<0.05), while there was no significant difference between T1 and T2 (P=0.65).

Conclusion: The study identified the core symptoms present at each stage of the perioperative period in patients with thyroid cancer, suggesting that clinical practitioners can develop efficient, targeted and precise management strategies based on the core symptoms at different times, with a view to improving the perioperative symptom experience of patients and increasing the efficiency of symptom management.

Clinical trial number: Not applicable.

甲状腺癌患者围手术期症状:横断面和纵向网络分析
背景:甲状腺癌患者在手术治疗期间会出现一系列症状。识别其核心症状,了解其动态变化,有助于提高临床症状管理的效率。方法:采用纵向观察研究设计,采用方便抽样方法,选取2024年10月至2025年4月在苏州市某三级医院甲状腺乳腺外科就诊的甲状腺癌患者。术前1天(T1)、术后1 ~ 2天(T2)、术后2周(T3)分别采用一般信息问卷和中文版记忆症状评估量表对患者进行评估。通过R语言构建症状严重程度偏倚相关网络,识别T1、T2和T3的核心症状。结果:本研究最终纳入248例甲状腺癌患者。结果显示,T1网络强度中心性最高的3种症状为食欲不振(rs=1.536)、焦虑(rs=1.442)和紧张(rs=1.439)。T2神经网络强度中心性最高的3种症状为手脚麻木/刺痛(rs=1.613)、食欲不振(rs=1.433)和恶心(rs=1.294)。T3网络强度中心性最高的3种症状为吞咽困难(rs=1.778)、感觉紧张(rs=1.681)和颈部不适(rs=1.520)。颈部不适(rs2=1.281, rs3=1.520)是术后较为稳定的核心症状。在网络结构不变性检验中,T1和T2之间存在显著差异(M=0.78, p)。本研究确定了甲状腺癌患者围手术期各阶段出现的核心症状,提示临床医生可根据不同时期的核心症状制定高效、有针对性、精准的管理策略,以改善患者的围手术期症状体验,提高症状管理效率。临床试验号:不适用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
BMC Endocrine Disorders
BMC Endocrine Disorders ENDOCRINOLOGY & METABOLISM-
CiteScore
4.40
自引率
0.00%
发文量
280
审稿时长
>12 weeks
期刊介绍: BMC Endocrine Disorders is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of endocrine disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
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