Radiofrequency ablation for symptomatic, non-functioning thyroid nodules: a single-center retrospective observational study.

IF 1.6 4区医学 Q3 SURGERY

Annals of Surgical Treatment and Research Pub Date : 2025-09-01 Epub Date: 2025-09-08 DOI:10.4174/astr.2025.109.3.144

Huiyin Zhu, Lifen Bai, Ming Zhou, Ling Zhou

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引用次数: 0

Abstract

Purpose: This study was designed to investigate the efficacy and safety of radiofrequency ablation (RFA) for treating thyroid nodules (TNs).

Methods: We retrospectively included the patients who underwent RFA for TNs in our hospital between January 2020 and December 2023. Preoperative and postoperative data including age, sex, body mass index, and thyroid hormone levels were collected from each patient. The efficacy of RFA on TNs was analyzed by evaluating the volume reduction (VR) and volume reduction rate (VRR) at postoperative months 1, 3, 6, and 12, respectively. In addition, the efficacy of RFA on nodule composition and postoperative complications was evaluated. Finally, a subgroup analysis was conducted to evaluate the potential risks.

Results: VR at postoperative month 12 was significantly higher than those at postoperative months 1, 3, and 6, respectively (all P < 0.001). VRR at month 12 was significantly higher than that of months 1, 3, and 6, respectively (all P < 0.001).

Conclusion: RFA is an effective option for treating TNs with good safety. VR and VRR showed significant increase after RFA compared with the pretreatment levels.

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射频消融治疗有症状的无功能甲状腺结节：一项单中心回顾性观察研究

目的：本研究旨在探讨射频消融（RFA）治疗甲状腺结节（TNs）的有效性和安全性。方法：我们回顾性纳入2020年1月至2023年12月期间在我院接受RFA治疗TNs的患者。收集每位患者的术前和术后数据，包括年龄、性别、体重指数和甲状腺激素水平。通过术后1、3、6、12个月的体积缩小（VR）和体积缩小率（VRR）来分析RFA治疗TNs的疗效。此外，我们还评估了RFA对结节组成和术后并发症的影响。最后进行亚组分析，评估潜在风险。结果：术后第12个月的VR明显高于术后第1、3、6个月（均P < 0.001）。第12个月的VRR分别显著高于第1、3、6个月（均P < 0.001）。结论：RFA是治疗TNs的有效选择，安全性好。RFA后的VR和VRR均较前处理水平显著升高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of Surgical Treatment and Research SURGERY-

CiteScore

2.30

自引率

7.10%

发文量

期刊介绍： Manuscripts to the Annals of Surgical Treatment and Research (Ann Surg Treat Res) should be written in English according to the instructions for authors. If the details are not described below, the style should follow the Uniform Requirements for Manuscripts Submitted to Biomedical Journals: Writing and Editing for Biomedical Publications available at International Committee of Medical Journal Editors (ICMJE) website (http://www.icmje.org).