Characterizing drug allergy management among allergists in Canada: a national survey study.

IF 2.4 4区 医学 Q2 ALLERGY
Erika Yue Lee, Brian Lee, Sinthiha Krishnan, Samira Jeimy, Matthieu Picard, Lana Rosenfield, Juan Ruiz, Christine Song
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引用次数: 0

Abstract

Background: Unverified drug allergy labels are common and associated with significant patient harm, yet infrastructure and testing practices vary across clinical settings in Canada.

Objective: To characterize variability in drug allergy management among allergists in Canada and identify setting-specific barriers to drug allergy testing and desensitization.

Methods: We developed a peer-reviewed 40-item survey, distributed via the Canadian Society of Allergy and Clinical Immunology, to assess practice patterns, testing modalities, and perceived barriers among allergists. Descriptive statistics and Fisher's exact test were used to evaluate responses by practice setting.

Results: Sixty-six allergists responded (30% estimated response rate), with 48.4% solely practicing in community clinics and 21.9% solely in hospital-based clinics. While 87.9% performed some form of drug allergy testing, hospital-based allergists were significantly more likely to perform intradermal (81.1% vs. 48.7%, p = 0.004) and patch testing (38.2% vs. 8.8%, p = 0.009), as well as non-oral drug challenges (63.6% vs. 20.0%, p = 0.0005). Common barriers included a lack of nursing support and inadequate reimbursement.

Conclusion: Drug allergy management practices vary substantially across Canada, with drug allergy testing being more frequently performed by allergists practicing in hospital-based clinics than by those in community-based clinics. Findings support the need for equitable access to testing infrastructure and system-level investments in improving drug allergy testing services.

加拿大过敏症专家药物过敏管理特征:一项全国性调查研究。
背景:未经证实的药物过敏标签很常见,并与严重的患者伤害有关,但加拿大临床环境的基础设施和测试实践各不相同。目的:了解加拿大过敏症专科医生药物过敏管理的差异,并确定药物过敏试验和脱敏的特定障碍。方法:我们开发了一项同行评议的40项调查,通过加拿大过敏和临床免疫学学会分发,以评估过敏症医师的实践模式、测试方式和感知障碍。采用描述性统计和Fisher精确检验对实践环境的反应进行评价。结果:66名过敏症专家有反应(30%的估计反应率),48.4%的人只在社区诊所执业,21.9%的人只在医院诊所执业。虽然有87.9%的人进行某种形式的药物过敏试验,但医院变态反应科医生更有可能进行皮内(81.1%对48.7%,p = 0.004)和斑贴试验(38.2%对8.8%,p = 0.009),以及非口服药物试验(63.6%对20.0%,p = 0.0005)。常见的障碍包括缺乏护理支持和报销不足。结论:加拿大各地的药物过敏管理实践差异很大,医院诊所的过敏症专家比社区诊所的过敏症专家更频繁地进行药物过敏试验。研究结果支持公平获得检测基础设施和系统级投资以改善药物过敏检测服务的必要性。
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来源期刊
CiteScore
4.30
自引率
3.70%
发文量
96
审稿时长
12 weeks
期刊介绍: Allergy, Asthma & Clinical Immunology (AACI), the official journal of the Canadian Society of Allergy and Clinical Immunology (CSACI), is an open access journal that encompasses all aspects of diagnosis, epidemiology, prevention and treatment of allergic and immunologic disease. By offering a high-visibility forum for new insights and discussions, AACI provides a platform for the dissemination of allergy and clinical immunology research and reviews amongst allergists, pulmonologists, immunologists and other physicians, healthcare workers, medical students and the public worldwide. AACI reports on basic research and clinically applied studies in the following areas and other related topics: asthma and occupational lung disease, rhinoconjunctivitis and rhinosinusitis, drug hypersensitivity, allergic skin diseases, urticaria and angioedema, venom hypersensitivity, anaphylaxis and food allergy, immunotherapy, immune modulators and biologics, immune deficiency and autoimmunity, T cell and B cell functions, regulatory T cells, natural killer cells, mast cell and eosinophil functions, complement abnormalities.
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