Treating resistant hypertension: What are the best pharmacologic options?

IF 0.8 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Jaapa-Journal of the American Academy of Physician Assistants Pub Date : 2025-10-01 Epub Date: 2025-09-25 DOI:10.1097/01.JAA.0000000000000249

Joseph M Walter, Andrew Giaquinto

引用次数: 0

Abstract

Abstract: Resistant hypertension (RH) is defined as blood pressure (BP) that remains above goal despite treatment with three first-line pharmacologic classes or BP that requires four or more medications to obtain control. After ruling out secondary causes and implementing nonpharmacologic treatments, clinicians may encounter the question of which pharmacologic treatment options should be used next. This article discusses evidence-based second-line medication options for RH.

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治疗顽固性高血压：最好的药物选择是什么？

摘要：顽固性高血压（RH）是指在接受三种一线药物治疗后血压仍高于目标，或需要四种或更多药物治疗才能控制血压。在排除继发原因和实施非药物治疗后，临床医生可能会遇到下一步应该使用哪种药物治疗方案的问题。本文讨论循证的RH二线药物选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Jaapa-Journal of the American Academy of Physician Assistants MEDICINE, GENERAL & INTERNAL-

CiteScore

1.20

自引率

9.10%

发文量

310

期刊介绍： JAAPA is the peer-reviewed clinical journal of the American Academy of Physician Assistants (AAPA). Published for more than 25 years, its mission is to support the ongoing education and advancement of physician assistants (PAs) by publishing current information and research on clinical, health policy, and professional issues. Published monthly, JAAPA''s award-winning editorial includes: -Clinical review articles (with AAPA-approved Category I CME in each issue)- Case reports- Clinical departments- Original health services research- Articles on issues of professional interest to PAs