Clinical Characteristics and Outcomes of Infective Endocarditis in Patients Undergoing Maintenance Hemodialysis　- A Retrospective Nationwide Database Analysis.

IF 3.7 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Circulation Journal Pub Date : 2025-09-23 DOI:10.1253/circj.CJ-25-0646

Kyo Kamisaka, Hiroshi Okamoto, Takeshi Nishi, Yoshitaka Sasahira, Koshiro Kanaoka, Yoko Sumita, Chisato Izumi, Shiro Uemura

引用次数: 0

Abstract

Background: Patients with infective endocarditis (IE) on maintenance hemodialysis (HD) have poor outcomes, but contemporary data remain limited.

Methods and results: We conducted a retrospective analysis using a nationwide Japanese administrative database and identified 12,158 patients hospitalized with IE between 2018 and 2021, including 806 (6.6%) on maintenance HD. The inhospital mortality rate was significantly higher in HD patients (30.0% vs. 13.5%, P<0.05).

Conclusions: Maintenance HD patients with IE had worse outcomes, underscoring the need for early recognition and tailored management in this highrisk group.

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维持性血液透析患者感染性心内膜炎的临床特征和结局——回顾性全国数据库分析。

背景：维持性血液透析（HD）的感染性心内膜炎（IE）患者预后较差，但目前的数据仍然有限。方法和结果：我们使用日本全国行政数据库进行了回顾性分析，确定了2018年至2021年期间因IE住院的12158例患者，其中806例（6.6%）为维持性HD。HD患者的住院死亡率明显更高（30.0% vs. 13.5%）。结论：维持性HD合并IE患者的预后更差，强调了对这一高危人群进行早期识别和量身定制管理的必要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Circulation Journal 医学-心血管系统

CiteScore

5.80

自引率

12.10%

发文量

471

审稿时长

1.6 months

期刊介绍： Circulation publishes original research manuscripts, review articles, and other content related to cardiovascular health and disease, including observational studies, clinical trials, epidemiology, health services and outcomes studies, and advances in basic and translational research.

Clinical Characteristics and Outcomes of Infective Endocarditis in Patients Undergoing Maintenance Hemodialysis - A Retrospective Nationwide Database Analysis.

Abstract

Clinical Characteristics and Outcomes of Infective Endocarditis in Patients Undergoing Maintenance Hemodialysis　- A Retrospective Nationwide Database Analysis.