Outcomes 10 Years After Implementing an Emergency Department Opt-out Bloodborne Virus Screening Program.

IF 3.8 4区医学 Q2 IMMUNOLOGY

Open Forum Infectious Diseases Pub Date : 2025-09-11 eCollection Date: 2025-09-01 DOI:10.1093/ofid/ofaf547

Liam Townsend, Fiona Herraghty, Seán Brennan, Conor Grant, Wenzhou Wang, Anne Moriarty, Yvonne Lynagh, Lorraine Clancy, Antoinette Power, Brendan Crowley, Suzanne Norris, Darragh Shields, Colm Bergin

{"title":"Outcomes 10 Years After Implementing an Emergency Department Opt-out Bloodborne Virus Screening Program.","authors":"Liam Townsend, Fiona Herraghty, Seán Brennan, Conor Grant, Wenzhou Wang, Anne Moriarty, Yvonne Lynagh, Lorraine Clancy, Antoinette Power, Brendan Crowley, Suzanne Norris, Darragh Shields, Colm Bergin","doi":"10.1093/ofid/ofaf547","DOIUrl":null,"url":null,"abstract":"Background: Bloodborne viruses (BBV) such as hepatitis B (HBV), hepatitis C (HCV), and HIV pose significant personal and public health risks. Screening and linkage to treating services are important tools in treatment and preventing onward transmission. This study reports outcomes of 10 years of an opt-out BBV screening program in a large urban emergency department (ED).Methods: Starting in July 2015, ED patients undergoing phlebotomy were offered routine BBV screening. We examine acceptance of screening, characteristics of new diagnoses, and onward linkage to care 10 years after program implementation. We also investigate factors associated with new viremic HCV diagnoses within this cohort to inform future service development.Results: Over the 10-year period, acceptance of BBV screening among phlebotomized patients was high (81%). There was no significant change in rates of new diagnoses of HIV, HBV, or HCV, but there was a significant reduction in polymerase chain reaction-positive HCV diagnoses. Linkage to care was high (96% HIV, 89% HBV, 95% HCV). Polymerase chain reaction-positive HCV was associated with people who inject drugs and being discharged directly from the ED.Conclusions: BBV screening in the ED demonstrates sustained acceptability, with a steady rate of new diagnoses detected. It provides high levels of linkage to care. It also identifies active HCV within a population of people who inject drugs attending the ED who are discharged directly without needing admission.","PeriodicalId":19517,"journal":{"name":"Open Forum Infectious Diseases","volume":"12 9","pages":"ofaf547"},"PeriodicalIF":3.8000,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12456172/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open Forum Infectious Diseases","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/ofid/ofaf547","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/9/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"IMMUNOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Bloodborne viruses (BBV) such as hepatitis B (HBV), hepatitis C (HCV), and HIV pose significant personal and public health risks. Screening and linkage to treating services are important tools in treatment and preventing onward transmission. This study reports outcomes of 10 years of an opt-out BBV screening program in a large urban emergency department (ED).

Methods: Starting in July 2015, ED patients undergoing phlebotomy were offered routine BBV screening. We examine acceptance of screening, characteristics of new diagnoses, and onward linkage to care 10 years after program implementation. We also investigate factors associated with new viremic HCV diagnoses within this cohort to inform future service development.

Results: Over the 10-year period, acceptance of BBV screening among phlebotomized patients was high (81%). There was no significant change in rates of new diagnoses of HIV, HBV, or HCV, but there was a significant reduction in polymerase chain reaction-positive HCV diagnoses. Linkage to care was high (96% HIV, 89% HBV, 95% HCV). Polymerase chain reaction-positive HCV was associated with people who inject drugs and being discharged directly from the ED.

Conclusions: BBV screening in the ED demonstrates sustained acceptability, with a steady rate of new diagnoses detected. It provides high levels of linkage to care. It also identifies active HCV within a population of people who inject drugs attending the ED who are discharged directly without needing admission.

查看原文本刊更多论文

急诊部选择退出血源性病毒筛查项目10年后的结果

背景：血源性病毒（BBV），如乙型肝炎（HBV）、丙型肝炎（HCV）和艾滋病毒构成重大的个人和公共健康风险。筛查和与治疗服务的联系是治疗和预防进一步传播的重要工具。本研究报告了一家大型城市急诊科（ED）选择退出BBV筛查项目10年的结果。方法：从2015年7月开始，对接受静脉切开术的ED患者进行常规BBV筛查。我们检查了筛查的接受程度，新诊断的特征，以及项目实施10年后与护理的联系。我们还研究了该队列中与新病毒型HCV诊断相关的因素，为未来的服务发展提供信息。结果：在10年期间，抽血患者接受BBV筛查的比例很高（81%）。HIV、HBV或HCV的新诊断率没有显著变化，但聚合酶链反应阳性的HCV诊断率有显著降低。与护理的相关性很高（96%为HIV， 89%为HBV， 95%为HCV）。聚合酶链反应阳性的丙型肝炎病毒与注射毒品和直接从急诊科出院的人有关。结论：在急诊科进行BBV筛查显示出持续的可接受性，新诊断率稳定。它提供了与护理的高水平联系。它还能识别出在急诊科直接出院而不需要入院的注射毒品人群中活跃的丙型肝炎病毒。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Open Forum Infectious Diseases Medicine-Neurology (clinical)

CiteScore

6.70

自引率

4.80%

发文量

630

审稿时长

9 weeks

期刊介绍： Open Forum Infectious Diseases provides a global forum for the publication of clinical, translational, and basic research findings in a fully open access, online journal environment. The journal reflects the broad diversity of the field of infectious diseases, and focuses on the intersection of biomedical science and clinical practice, with a particular emphasis on knowledge that holds the potential to improve patient care in populations around the world. Fully peer-reviewed, OFID supports the international community of infectious diseases experts by providing a venue for articles that further the understanding of all aspects of infectious diseases.