PikMe: A flexible prioritization tool for chemicals of emerging concern.

Abstract

Identifying new contaminants of emerging concern remains a complex task due to the sheer number of chemical substances potentially released into the environment, the scattered sources of information and often the lack of adequate data. Environmental screening and monitoring programs are designed to map the presence, sources, and potential environmental impacts of contaminants, yet prioritising which chemicals to include in such efforts remains resource-intensive and technically challenging. PikMe is a modular, open-access prioritization tool that integrates information from major data bases and evaluates the concern and reliability of the data for more than one million substances. PikMe is built in a modular way so that prioritization can be done based on specific chemical properties relevant to a given scenario (ie, drinking water contaminants or bioaccumulation in biota) rather than assigning only a global risk score. PikMe scores substances based on persistence, bioaccumulation, mobility, environmental toxicity, and human toxicity, assigning individual score per property. Additionally, PikMe is designed for flexibility by allowing the integration of external lists of chemicals and supporting optional add-ons. Different scenarios of use are described in this paper, including the selection of chemicals for environmental monitoring and screening in Norway and the assessment of the implications of the new classifications according to Regulation for Classification, Labelling and Packaging of substances and mixtures (CLP) on persistent chemicals.