How to deal with lower gastrointestinal defects: the role of endoscopy.

IF 3.3 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Expert Review of Gastroenterology & Hepatology Pub Date : 2025-10-01 Epub Date: 2025-10-29 DOI:10.1080/17474124.2025.2564388

Maria Valeria Matteo, Giulia Santi, Vincenzo Bove, Martina De Siena, Loredana Gualtieri, Valerio Pontecorvi, Federico Barbaro, Cristiano Spada, Ivo Boškoski

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引用次数: 0

Abstract

Introduction: Lower gastrointestinal (GI) defects, including leaks, perforations, and fistulas, pose significant challenges for diagnosis and management. These conditions are associated with high morbidity and mortality rates, necessitating effective treatment strategies to restore GI continuity and improve patient outcomes.

Areas covered: This special report examines current evidence and future perspectives on the endoscopic management of lower GI defects. A literature search was conducted in PubMed, Google Scholar, and Scopus for studies published up to July 2025 that focused on the endoscopic management of lower GI defects. It provides an overview of various endoscopic techniques, including clips, endosuturing, stents, endoscopic internal drainage, endoscopic vacuum therapy, and emerging regenerative approaches, and their underlying advantages and limitations. The need for more standardized and larger studies to establish guidelines has been addressed.

Expert opinion: Endoscopy is increasingly being recognized as a therapeutic option for lower GI defects, offering less invasive alternatives to traditional surgery. The challenges in developing standardized protocols are due to diverse clinical scenarios and limited prospective data. Future advancements are expected in technologies and personalization of treatments. A multidisciplinary approach is essential to achieve optimal outcomes in this complex field.

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如何处理下消化道缺陷：内镜的作用。

下胃肠道（GI）缺陷，包括渗漏、穿孔和瘘管，对诊断和治疗提出了重大挑战。这些疾病与高发病率和死亡率相关，需要有效的治疗策略来恢复胃肠道的连续性并改善患者的预后。涵盖领域：这篇特别报告探讨了内镜下消化道缺陷治疗的现有证据和未来观点。我们在PubMed、b谷歌Scholar和Scopus中检索了截至2025年7月发表的关于下消化道缺陷的内镜治疗的研究。它提供了各种内窥镜技术的概述，包括夹，插管，支架，内窥镜内引流，内窥镜真空治疗和新兴的再生方法，以及它们潜在的优势和局限性。需要更标准化和更大规模的研究来建立指导方针的问题已经得到解决。专家意见：内窥镜检查越来越被认为是治疗下消化道缺陷的一种选择，它提供了比传统手术侵入性更小的选择。制定标准化方案的挑战是由于不同的临床情况和有限的前瞻性数据。技术和个性化治疗有望在未来取得进展。一个多学科的方法是必不可少的，以达到最佳结果，在这个复杂的领域。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Expert Review of Gastroenterology & Hepatology GASTROENTEROLOGY & HEPATOLOGY-

CiteScore

6.80

自引率

2.60%

发文量

审稿时长

6-12 weeks

期刊介绍： The enormous health and economic burden of gastrointestinal disease worldwide warrants a sharp focus on the etiology, epidemiology, prevention, diagnosis, treatment and development of new therapies. By the end of the last century we had seen enormous advances, both in technologies to visualize disease and in curative therapies in areas such as gastric ulcer, with the advent first of the H2-antagonists and then the proton pump inhibitors - clear examples of how advances in medicine can massively benefit the patient. Nevertheless, specialists face ongoing challenges from a wide array of diseases of diverse etiology.