The current epidemic status and prevention and control of bovine viral diarrhea virus in yaks in China.

IF 4.8 2区医学 Q2 IMMUNOLOGY

Frontiers in Cellular and Infection Microbiology Pub Date : 2025-09-09 eCollection Date: 2025-01-01 DOI:10.3389/fcimb.2025.1647328

Zhi Li, Yuan Han, Qing Yuan, Shuqin Wang, Changjiang Chen, Shandian Gao, Ru Meng

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引用次数: 0

Abstract

In China, yaks are predominantly distributed across the Qinghai-Tibet Plateau and surrounding high-altitude regions, including Tibet, Qinghai, Sichuan, Gansu, Xinjiang and Yunnan. These animals serve as multifunctional resources for local herders, providing meat, dairy, hides, and wool, while also constituting a critical component of the industrial chain in high-altitude ecosystems. Recent epidemiological studies have demonstrated an increasing trend in bovine viral diarrhea virus (BVDV) infection rates among yak populations in provinces such as Gansu, Sichuan, Tibet, and Qinghai. This review not only summarizes the epidemiological status, distribution of viral sub-genotypes, and current prevention and control in yaks across various regions, but also proposes, for the first time, a systematic "Five-dimensional Integration" comprehensive prevention and control model for BVDV, including vaccine breakthrough, precise monitoring, dynamic early warning, population purification, and active prevention, which will provide directed insight for the prevention and control strategies of yaks infected by BVDV.

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中国牦牛病毒性腹泻病毒流行现状及防治

这些动物是当地牧民的多功能资源，提供肉类、乳制品、兽皮和羊毛，同时也是高海拔生态系统产业链的重要组成部分。综述了各地区牦牛BVDV流行病学现状、病毒亚基因型分布及防控现状，并首次提出了包括疫苗突破、精准监测、动态预警、种群净化、主动预防在内的系统的BVDV“五维一体”综合防控模式。这将为牦牛BVDV感染的防控策略提供有指导意义的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Frontiers in Cellular and Infection Microbiology IMMUNOLOGY-MICROBIOLOGY

CiteScore

7.90

自引率

7.00%

发文量

1817

审稿时长

14 weeks

期刊介绍： Frontiers in Cellular and Infection Microbiology is a leading specialty journal, publishing rigorously peer-reviewed research across all pathogenic microorganisms and their interaction with their hosts. Chief Editor Yousef Abu Kwaik, University of Louisville is supported by an outstanding Editorial Board of international experts. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. Frontiers in Cellular and Infection Microbiology includes research on bacteria, fungi, parasites, viruses, endosymbionts, prions and all microbial pathogens as well as the microbiota and its effect on health and disease in various hosts. The research approaches include molecular microbiology, cellular microbiology, gene regulation, proteomics, signal transduction, pathogenic evolution, genomics, structural biology, and virulence factors as well as model hosts. Areas of research to counteract infectious agents by the host include the host innate and adaptive immune responses as well as metabolic restrictions to various pathogenic microorganisms, vaccine design and development against various pathogenic microorganisms, and the mechanisms of antibiotic resistance and its countermeasures.