Utilizing a Laser Monitoring-Based Method for Solubility and Thermodynamics Study of Isophthalic Acid in Aqueous Mixtures of 1-Propanol/2-Propanol

Abstract

This study investigated the solubility of isophthalic acid in binary mixtures of 1-propanol/2-propanol and water, across temperatures from 298.2 to 313.2 K. The solubility was determined using a laser-based robotic system. The resulting solubility data were analyzed through various mathematical models, including the van’t Hoff, Jouyban–Acree, Jouyban–Acree–van’t Hoff, mixture response surface, and modified Wilson models. The experimental data on isophthalic acid dissolution included several thermodynamic properties such as ΔG°, ΔH°, ΔS°, and TΔS°. These properties provided important insights into the energetic aspects of the dissolution process and were calculated using the van’t Hoff equation.