{"title":"Leveraging Thematic Relationships Between Verbs and Nouns for Noun Retrieval Treatment in Logopenic Primary Progressive Aphasia: A Case Series.","authors":"Fatima Jebahi, Aneta Kielar","doi":"10.1044/2025_AJSLP-25-00107","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>This study examined the effects of a multimodal verb-centered noun retrieval treatment in three individuals with logopenic variant primary progressive aphasia (lvPPA). The intervention aimed to improve naming accuracy for trained nouns and promote generalization to untrained nouns.</p><p><strong>Method: </strong>Three individuals with lvPPA participated in a multiple-baseline design study. Treatment was based on thematic relationships between verbs and nouns, incorporated self-cueing strategies, and orthographic homework practice, adapted from the Copy and Recall Treatment. Naming accuracy for treated and untreated nouns was assessed pretreatment and posttreatment to evaluate gains on the treated items and generalization effects.</p><p><strong>Results: </strong>All participants demonstrated statistically significant improvements in naming accuracy for treated nouns, with large effect sizes. Generalization to untrained nouns was also observed in all participants but varied across participants, with the greatest gains observed in the individual with milder baseline impairments. The intervention, centered on verbs and their thematic roles, appeared to support lexical access of nouns and homework practice reinforced retrieval. The treatment effects and generalization were most robust for the individual with less-affected phonological manipulation and semantic processing abilities of nouns and verbs.</p><p><strong>Conclusions: </strong>Findings support the efficacy of a structured lexical retrieval intervention in lvPPA that leverages verb-noun thematic relationships and self-cueing strategies. Individual differences in baseline cognitive-linguistic skills and performance on sematic association tasks may influence treatment responsiveness. Future research should explore predictors of treatment response and assess long-term maintenance of gains to refine intervention approaches for lvPPA.</p><p><strong>Supplemental material: </strong>https://doi.org/10.23641/asha.30082309.</p>","PeriodicalId":49240,"journal":{"name":"American Journal of Speech-Language Pathology","volume":" ","pages":"1-18"},"PeriodicalIF":2.5000,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of Speech-Language Pathology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1044/2025_AJSLP-25-00107","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: This study examined the effects of a multimodal verb-centered noun retrieval treatment in three individuals with logopenic variant primary progressive aphasia (lvPPA). The intervention aimed to improve naming accuracy for trained nouns and promote generalization to untrained nouns.
Method: Three individuals with lvPPA participated in a multiple-baseline design study. Treatment was based on thematic relationships between verbs and nouns, incorporated self-cueing strategies, and orthographic homework practice, adapted from the Copy and Recall Treatment. Naming accuracy for treated and untreated nouns was assessed pretreatment and posttreatment to evaluate gains on the treated items and generalization effects.
Results: All participants demonstrated statistically significant improvements in naming accuracy for treated nouns, with large effect sizes. Generalization to untrained nouns was also observed in all participants but varied across participants, with the greatest gains observed in the individual with milder baseline impairments. The intervention, centered on verbs and their thematic roles, appeared to support lexical access of nouns and homework practice reinforced retrieval. The treatment effects and generalization were most robust for the individual with less-affected phonological manipulation and semantic processing abilities of nouns and verbs.
Conclusions: Findings support the efficacy of a structured lexical retrieval intervention in lvPPA that leverages verb-noun thematic relationships and self-cueing strategies. Individual differences in baseline cognitive-linguistic skills and performance on sematic association tasks may influence treatment responsiveness. Future research should explore predictors of treatment response and assess long-term maintenance of gains to refine intervention approaches for lvPPA.
期刊介绍：
Mission: AJSLP publishes peer-reviewed research and other scholarly articles on all aspects of clinical practice in speech-language pathology. The journal is an international outlet for clinical research pertaining to screening, detection, diagnosis, management, and outcomes of communication and swallowing disorders across the lifespan as well as the etiologies and characteristics of these disorders. Because of its clinical orientation, the journal disseminates research findings applicable to diverse aspects of clinical practice in speech-language pathology. AJSLP seeks to advance evidence-based practice by disseminating the results of new studies as well as providing a forum for critical reviews and meta-analyses of previously published work.
Scope: The broad field of speech-language pathology, including aphasia; apraxia of speech and childhood apraxia of speech; aural rehabilitation; augmentative and alternative communication; cognitive impairment; craniofacial disorders; dysarthria; fluency disorders; language disorders in children; speech sound disorders; swallowing, dysphagia, and feeding disorders; and voice disorders.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
