Risk factors of frailty/sarcopenia in community older adults: Meta-analysis.

IF 1.6 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Open Medicine Pub Date : 2025-09-12 eCollection Date: 2025-01-01 DOI:10.1515/med-2025-1259

Xiaoyang Yan, Jiansong Zhou, Xia Cao

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引用次数: 0

Abstract

Objective: This study aimed to review the rates of physical frailty and sarcopenia, as well as associated risk factors, among adults aged 60 and older living in the community.

Methods: A systematic literature search was conducted in PubMed, Wiley Library, Embase, Web of Science, and Cochrane Library for articles published from January 2000 to December 2024. The review followed PRISMA guidelines for meta-analysis.

Results: Sixteen studies with 41,765 participants were included in the meta-analysis. The pooled prevalence of frailty/sarcopenia was 27% (95% CI: 19-35%). Specifically, the pooled prevalence of frailty was 25% (95% CI: 16-38%) and that of sarcopenia was 23% (95% CI: 13-37%). Age, malnutrition, depression, falls, and hypertension were identified as significant risk factors for frailty/sarcopenia.

Conclusion: Nearly 30% of older adults in the community are affected by frailty/sarcopenia. Early identification of these risk factors is crucial for the prevention and management of frailty/sarcopenia. Further research is needed to determine effective interventions and strategies to reduce the incidence of frailty/sarcopenia.

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社区老年人虚弱/肌肉减少症的危险因素：荟萃分析

目的：本研究旨在回顾60岁及以上生活在社区的成年人身体虚弱和肌肉减少症的发生率，以及相关的危险因素。方法：系统检索PubMed、Wiley Library、Embase、Web of Science和Cochrane Library中2000年1月至2024年12月发表的文章。该综述遵循PRISMA的meta分析指南。结果：meta分析包括16项研究，41765名参与者。虚弱/肌肉减少症的总患病率为27% （95% CI: 19-35%）。具体来说，虚弱的总患病率为25% (95% CI: 16-38%)，肌肉减少症的总患病率为23% （95% CI: 13-37%）。年龄、营养不良、抑郁、跌倒和高血压被认为是虚弱/肌肉减少症的重要危险因素。结论：社区中近30%的老年人受到虚弱/肌肉减少症的影响。早期识别这些危险因素对于预防和管理虚弱/肌肉减少症至关重要。需要进一步的研究来确定有效的干预措施和策略来减少虚弱/肌肉减少症的发生率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Open Medicine Medicine-General Medicine

CiteScore

3.00

自引率

0.00%

发文量

153

审稿时长

20 weeks

期刊介绍： Open Medicine is an open access journal that provides users with free, instant, and continued access to all content worldwide. The primary goal of the journal has always been a focus on maintaining the high quality of its published content. Its mission is to facilitate the exchange of ideas between medical science researchers from different countries. Papers connected to all fields of medicine and public health are welcomed. Open Medicine accepts submissions of research articles, reviews, case reports, letters to editor and book reviews.