{"title":"The effect of mangosteen rind extract nanocapsule as a feed additive on the growth performance and blood lipid profile of broiler chicken.","authors":"Andri Kusmayadi, Richa Mardianingrum, Dwi Wijayanti, Yanti Yanti","doi":"10.5455/OVJ.2025.v15.i6.44","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Nanoencapsulation technology has great potential as an innovation in animal feed, especially as a natural supplement to replace antibiotics and improve livestock health. With this technology, the bioactive benefits of mangosteen rind can be utilized more optimally, opening up new opportunities in the sustainable livestock industry, especially for poultry nutrition.</p><p><strong>Aim: </strong>This study aimed to examine the effect of adding mangosteen rind extract nanocapsule (MREN) as a feed additive and to determine its optimal level for improving the growth performance and blood lipid profile of broiler chicken.</p><p><strong>Methods: </strong>The research design was completely randomized with a one-way pattern. There were 300 DOC unsexed Cobb strain broiler chickens grouped into 5 feed treatments: T0:100% basal feed (BF) as a negative control, T1:100% BF + zinc-bacitracin 50 ppm (positive control), T2: BF + 0.1% MREN, T3: BF + 0.2% MREN, and T4: BF + 0.3% MREN. The treatment was repeated 6 times and each experimental cage was filled with 10 broiler chickens. The maintenance was conducted for 35 days to observe the growth performance and blood lipid profile of broiler chickens. <b>Results:</b> The results showed that the addition of mangosteen rind extract nanocapsules had a significant effect on the body weight, body weight gain (BWG), and feed conversion ratio and blood lipid profile of broiler chickens (triglycerides and HDL). Feed treatments containing 0.1% and 0.2% mangosteen rind extract nanocapsules (T2 and T3) produced better growth performance than T0 with an increase in body weight, BWG, and feed conversion has a value of 16.71-23.08 g, 17.26-21.14 g, and 0.05-0.07, respectively. For the blood lipid profile, T4 treatment at a dose of 0.3% was able to decrease triglyceride levels by 193.95 g compared with T0, whereas T2 treatment at a dose of 0.1% was able to increase HDL levels by 6.35 mg/dl.</p><p><strong>Conclusion: </strong>The addition of mangosteen rind extract nanocapsules at low level (0.1%-0.2%) is recommended for broiler chickens to improve growth performance and blood lipid profiles.</p>","PeriodicalId":19531,"journal":{"name":"Open Veterinary Journal","volume":"15 6","pages":"2762-2773"},"PeriodicalIF":1.0000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12451187/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open Veterinary Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5455/OVJ.2025.v15.i6.44","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/6/30 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Nanoencapsulation technology has great potential as an innovation in animal feed, especially as a natural supplement to replace antibiotics and improve livestock health. With this technology, the bioactive benefits of mangosteen rind can be utilized more optimally, opening up new opportunities in the sustainable livestock industry, especially for poultry nutrition.
Aim: This study aimed to examine the effect of adding mangosteen rind extract nanocapsule (MREN) as a feed additive and to determine its optimal level for improving the growth performance and blood lipid profile of broiler chicken.
Methods: The research design was completely randomized with a one-way pattern. There were 300 DOC unsexed Cobb strain broiler chickens grouped into 5 feed treatments: T0:100% basal feed (BF) as a negative control, T1:100% BF + zinc-bacitracin 50 ppm (positive control), T2: BF + 0.1% MREN, T3: BF + 0.2% MREN, and T4: BF + 0.3% MREN. The treatment was repeated 6 times and each experimental cage was filled with 10 broiler chickens. The maintenance was conducted for 35 days to observe the growth performance and blood lipid profile of broiler chickens. Results: The results showed that the addition of mangosteen rind extract nanocapsules had a significant effect on the body weight, body weight gain (BWG), and feed conversion ratio and blood lipid profile of broiler chickens (triglycerides and HDL). Feed treatments containing 0.1% and 0.2% mangosteen rind extract nanocapsules (T2 and T3) produced better growth performance than T0 with an increase in body weight, BWG, and feed conversion has a value of 16.71-23.08 g, 17.26-21.14 g, and 0.05-0.07, respectively. For the blood lipid profile, T4 treatment at a dose of 0.3% was able to decrease triglyceride levels by 193.95 g compared with T0, whereas T2 treatment at a dose of 0.1% was able to increase HDL levels by 6.35 mg/dl.
Conclusion: The addition of mangosteen rind extract nanocapsules at low level (0.1%-0.2%) is recommended for broiler chickens to improve growth performance and blood lipid profiles.
期刊介绍：
Open Veterinary Journal is a peer-reviewed international open access online and printed journal that publishes high-quality original research articles. reviews, short communications and case reports dedicated to all aspects of veterinary sciences and its related subjects. Research areas include the following: Infectious diseases of zoonotic/food-borne importance, applied biochemistry, parasitology, endocrinology, microbiology, immunology, pathology, pharmacology, physiology, epidemiology, molecular biology, immunogenetics, surgery, ophthalmology, dermatology, oncology and animal reproduction. All papers are peer-reviewed. Moreover, with the presence of well-qualified group of international referees, the process of publication will be done meticulously and to the highest standards.
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