Blackleg: A deadly disease with a hidden cause.

IF 1 Q3 VETERINARY SCIENCES
Open Veterinary Journal Pub Date : 2025-06-01 Epub Date: 2025-06-30 DOI:10.5455/OVJ.2025.v15.i6.7
Wiwiek Tyasningsih, Aswin Rafif Khairullah, John Yew Huat Tang, Mustofa Helmi Effendi, Saifur Rehman, Ilma Fauziah Ma'ruf, Bantari Wisynu Kusuma Wardhani, Ikechukwu Benjamin Moses, Budiastuti Budiastuti, Kartika Afrida Fauzia, Riza Zainuddin Ahmad, Ima Fauziah, Muhammad Khaliim Jati Kusala, Bima Putra Pratama, Dea Anita Ariani Kurniasih, Syahputra Wibowo
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引用次数: 0

Abstract

Blackleg is an infectious disease that mainly affects cattle and rarely affects other ruminants. It is characterized by hemorrhagic blackleg myositis. Clostridium chauvoei is a highly pathogenic anaerobic, endospore-forming Gram- positive bacteria that causes blackleg disease. Blackleg disease was first reported in 1870, but the causative bacterium C. chauvoei was not described until 1887. Clostridium chauvoei is found in grassland, fresh water, silage, soil, and the excrement of healthy animals. Cattle intestines and pasture soil have both been found to contain C. chauvoei spores, suggesting that the infection is contracted by ingesting the spores. Significant lesions are less common in the heart and more common in the skeletal muscle. Anaerobic culture, polymerase chain reaction, immunodetection using fluorescent antibody tests, and immunohistochemistry are methods for identifying bacteria. The production of gas in animal tissues, known as emphysematous swelling, is a hallmark of blackleg illness. Swelling usually affects big muscles including the neck, shoulders, thighs, and hips. Most incidences of blackleg illness in cattle occur during the warmer months of the year, and the disease typically manifests seasonally. Penicillin treatment and surgical removal of the lesions, including fasciotomy, are recommended for infected animals that are not in danger of death. Vaccination is a crucial part of the health management of many livestock production enterprises and can prevent blackleg illness. Blackleg disease can be controlled by destroying the carcass and burning the top layer of soil to eradicate any remaining spores.

黑腿病:一种病因不明的致命疾病。
黑腿病是一种主要影响牛的传染病,很少影响其他反刍动物。其特点是出血性黑腿肌炎。chauvoei梭状芽胞杆菌是一种高致病性厌氧,芽孢内形成革兰氏阳性细菌,引起黑腿病。黑腿病于1870年首次报道,但直到1887年才描述了致病细菌C. chauvoei。萧氏梭状芽孢杆菌存在于草地、淡水、青贮饲料、土壤和健康动物的粪便中。牛肠和牧场土壤都发现含有chauvoei孢子,这表明这种感染是通过摄入孢子而感染的。明显的病变在心脏不太常见,在骨骼肌中更常见。厌氧培养、聚合酶链反应、荧光抗体检测和免疫组织化学是鉴定细菌的方法。动物组织产生气体,称为肺气肿性肿胀,是黑腿病的标志。肿胀通常影响大块肌肉,包括颈部、肩部、大腿和臀部。牛黑腿病的大多数发病率发生在一年中较温暖的月份,并且该疾病通常表现为季节性。对于没有死亡危险的受感染动物,建议采用青霉素治疗和手术切除病变,包括筋膜切开术。接种疫苗是许多畜牧生产企业卫生管理的重要组成部分,可以预防黑腿病。黑腿病可以通过摧毁尸体和燃烧土壤表层来消灭任何剩余的孢子来控制。
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来源期刊
Open Veterinary Journal
Open Veterinary Journal VETERINARY SCIENCES-
CiteScore
1.40
自引率
0.00%
发文量
112
审稿时长
12 weeks
期刊介绍: Open Veterinary Journal is a peer-reviewed international open access online and printed journal that publishes high-quality original research articles. reviews, short communications and case reports dedicated to all aspects of veterinary sciences and its related subjects. Research areas include the following: Infectious diseases of zoonotic/food-borne importance, applied biochemistry, parasitology, endocrinology, microbiology, immunology, pathology, pharmacology, physiology, epidemiology, molecular biology, immunogenetics, surgery, ophthalmology, dermatology, oncology and animal reproduction. All papers are peer-reviewed. Moreover, with the presence of well-qualified group of international referees, the process of publication will be done meticulously and to the highest standards.
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