Breastfeeding determinants in Egyptian mothers with systemic lupus erythematosus or rheumatoid arthritis: a retrospective cohort study.

IF 3.5 2区医学 Q1 RHEUMATOLOGY

Lupus Science & Medicine Pub Date : 2025-09-22 DOI:10.1136/lupus-2025-001733

Omima Ahmed El-Farra, Amal Mohamed Elmesiry, Hager Adel Yehia Abdelfattah, Nermeen Mohammed Elmenayar, Ahmed Adel Abdel Azim, Ahmed Ibrahim Ewais, Gamal Saeed Gamal, Abrar Ghassan Mousa Balousha, Alaa Ali Awad

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引用次数: 0

Abstract

Objective: Breastfeeding prevalence and challenges among women of systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) is under-researched especially in the Middle East-North Africa region. This study aimed to assess breastfeeding initiation, duration and predictors of early discontinuation (<6 months post partum) among Egyptian mothers with SLE or RA.

Methods: This multicentre retrospective cohort study included 320 pregnancies: 62 SLE (105 pregnancies), 71 RA (110 pregnancies) and 59 healthy mothers (105 pregnancies). Data on pregnancy history, breastfeeding intent, initiation, duration and weaning reasons were collected.

Results: Exclusive breastfeeding was lowest in SLE (29.9%) vs RA (50.6%) and controls (60%, p<0.001). Continuation beyond 6 months was significantly lower in SLE (36.2%) and RA (33.6%) vs controls (81%, p<0.001). Postpartum depression independently predicted discontinuation in SLE (adjusted OR (aOR)=0.06, 95% CI 0.01 to 0.6) and RA (aOR=0.34, 95% CI 0.13 to 0.9). Multivariable generalised estimating equation confirmed SLE reduced breastfeeding odds versus controls (aOR=0.41, p=0.040).

Conclusion: Breastfeeding is significantly less prevalent among Egyptian mothers with SLE and RA when compared with control group. Targeted educational programme and support may help improve breastfeeding rates in SLE/RA mothers.

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母乳喂养决定因素在埃及母亲与系统性红斑狼疮或类风湿关节炎：回顾性队列研究。

目的：对系统性红斑狼疮（SLE）和类风湿性关节炎（RA）妇女母乳喂养的患病率和挑战进行了研究，特别是在中东-北非地区。本研究旨在评估母乳喂养的开始、持续时间和早期停止的预测因素(方法：本多中心回顾性队列研究包括320例妊娠：62例SLE（105例妊娠），71例RA（110例妊娠）和59例健康母亲（105例妊娠）。收集了有关妊娠史、母乳喂养意图、开始、持续时间和断奶原因的数据。结果：纯母乳喂养在SLE（29.9%）中最低，而在RA（50.6%）和对照组（60%）中最低。结论：与对照组相比，母乳喂养在SLE和RA的埃及母亲中明显较低。有针对性的教育计划和支持可能有助于提高SLE/RA母亲的母乳喂养率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Lupus Science & Medicine RHEUMATOLOGY-

CiteScore

5.30

自引率

7.70%

发文量

审稿时长

15 weeks

期刊介绍： Lupus Science & Medicine is a global, peer reviewed, open access online journal that provides a central point for publication of basic, clinical, translational, and epidemiological studies of all aspects of lupus and related diseases. It is the first lupus-specific open access journal in the world and was developed in response to the need for a barrier-free forum for publication of groundbreaking studies in lupus. The journal publishes research on lupus from fields including, but not limited to: rheumatology, dermatology, nephrology, immunology, pediatrics, cardiology, hepatology, pulmonology, obstetrics and gynecology, and psychiatry.