Surveillance Visits for Ovarian Cancer: Is It Time to Reconsider?

IF 1.9 3区医学 Q3 ONCOLOGY

Journal of Surgical Oncology Pub Date : 2025-09-24 DOI:10.1002/jso.70099

Sharonne Holtzman, Caroline Gellman, Isabel Chess, Riva Letchinger, Lily McCarthy, Alexis Zachem, Guillaume Stoffels, Stephanie V Blank, Valentin Kolev

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引用次数: 0

Abstract

Background and objectives: The objective of this study was to examine patterns of recurrence and presentation of ovarian cancer (OC) patients.

Methods: This was a retrospective review of all patients at a single academic institution diagnosed with OC between January 1, 2014, and December 31, 2022. Demographic and clinical characteristics were extracted. Cox proportional hazards models were utilized to compare these characteristics, while the Kaplan-Meier method was employed to determine overall survival (OS).

Results: During our study, 437 patients were diagnosed with OC, and 173 (39.6%) were diagnosed with recurrence. For those diagnosed with recurrence, 68 (39.3%) were symptomatic. Forty-eight (72.7%) symptomatic patients had abdominal pain or increased abdominal girth, 5 (7.6%) had shortness of breath, 1 (1.5%) had vaginal bleeding, and 12 (18.1%) had nonspecific symptoms. Among the 105 (60.7%) asymptomatic patients, 57 (54.3%) had increasing CA-125 levels. Four (2.32%) patients with recurrence were diagnosed on a routine pelvic exam, and only one (0.5%) patient was asymptomatic and incidentally diagnosed.

Conclusions: The majority of patients were asymptomatic at the time of diagnosis, and the pelvic exam was not the primary means of detecting OC recurrence. Guidelines for surveillance visits for OC patients and the utility of a pelvic exam should be examined.

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卵巢癌的监测访问：是时候重新考虑了吗？

背景和目的：本研究的目的是研究卵巢癌（OC）患者的复发和表现模式。方法：回顾性分析2014年1月1日至2022年12月31日在一家学术机构诊断为OC的所有患者。提取人口学和临床特征。Cox比例风险模型用于比较这些特征，Kaplan-Meier法用于确定总生存期（OS）。结果：在本研究中，437例患者被诊断为OC， 173例（39.6%）被诊断为复发。在诊断为复发的患者中，68例（39.3%）出现症状。有症状的患者48例（72.7%）出现腹痛或腹围增大，5例（7.6%）出现呼吸急促，1例（1.5%）出现阴道出血，12例（18.1%）出现非特异性症状。在105例（60.7%）无症状患者中，57例（54.3%）CA-125水平升高。4例（2.32%）复发患者在常规盆腔检查中被诊断出来，只有1例（0.5%）患者无症状和偶然诊断。结论：大多数患者在诊断时无症状，盆腔检查不是检测卵巢癌复发的主要手段。对于卵巢癌患者的监测访问指南和盆腔检查的效用应该进行检查。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Surgical Oncology 医学-外科

CiteScore

4.70

自引率

4.00%

发文量

367

审稿时长

2 months

期刊介绍： The Journal of Surgical Oncology offers peer-reviewed, original papers in the field of surgical oncology and broadly related surgical sciences, including reports on experimental and laboratory studies. As an international journal, the editors encourage participation from leading surgeons around the world. The JSO is the representative journal for the World Federation of Surgical Oncology Societies. Publishing 16 issues in 2 volumes each year, the journal accepts Research Articles, in-depth Reviews of timely interest, Letters to the Editor, and invited Editorials. Guest Editors from the JSO Editorial Board oversee multiple special Seminars issues each year. These Seminars include multifaceted Reviews on a particular topic or current issue in surgical oncology, which are invited from experts in the field.