Advances in the use of dietary β-glucan in aquaculture: Structural insights, immunological benefits, and feed applications

IF 2.4 3区农林科学 Q1 FISHERIES

Developmental and comparative immunology Pub Date : 2025-09-21 DOI:10.1016/j.dci.2025.105476

Yue Kong , Saikun Pan , Shengjun Wu

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引用次数: 0

Abstract

β-glucan, a bioactive polysaccharide derived from fungi, yeast, grains, and algae, has become a versatile element in aquaculture feeding. This review thoroughly examines the structural differences, extraction techniques, and purification methods of β-glucans, correlating these characteristics with their biological effectiveness. Particular attention is given to their antioxidant, immunomodulatory, antibacterial, and hypolipidemic properties, along with their integration into functional diets to enhance aquatic animal performance. β-glucan supplementation has demonstrated effectiveness in enhancing development, augmenting disease resistance, and fortifying stress tolerance in many aquatic species by altering innate immunity, oxidative equilibrium, and metabolic functions. The fundamental mechanisms, encompassing receptor-mediated signaling pathways and dose-dependent responses, are meticulously examined. Furthermore, issues pertaining to delivery techniques, structural integrity, and practical use are examined. This investigation underscores β-glucan as a viable and sustainable substitute for antibiotics in enhancing aquaculture health and productivity.

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饲料中β-葡聚糖在水产养殖中的应用进展：结构见解、免疫效益和饲料应用。

β-葡聚糖是一种从真菌、酵母、谷物和藻类中提取的生物活性多糖，已成为水产养殖饲料中的多功能元素。本文综述了β-葡聚糖的结构差异、提取技术和纯化方法，并将这些特性与它们的生物学有效性联系起来。特别关注的是它们的抗氧化、免疫调节、抗菌和降血脂特性，以及它们与功能性饲料的结合，以提高水生动物的生产性能。在许多水生物种中，β-葡聚糖补充剂已被证明可以通过改变先天免疫、氧化平衡和代谢功能来促进发育、增强抗病性和增强抗逆性。基本机制，包括受体介导的信号通路和剂量依赖性反应，仔细检查。此外，有关交付技术，结构完整性和实际使用的问题进行了审查。本研究强调β-葡聚糖在提高水产养殖健康和生产力方面是一种可行和可持续的抗生素替代品。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Developmental and comparative immunology 医学-动物学

CiteScore

6.20

自引率

6.90%

发文量

206

审稿时长

49 days

期刊介绍： Developmental and Comparative Immunology (DCI) is an international journal that publishes articles describing original research in all areas of immunology, including comparative aspects of immunity and the evolution and development of the immune system. Manuscripts describing studies of immune systems in both vertebrates and invertebrates are welcome. All levels of immunological investigations are appropriate: organismal, cellular, biochemical and molecular genetics, extending to such fields as aging of the immune system, interaction between the immune and neuroendocrine system and intestinal immunity.