Demographically adjusted normative data among Peruvians with diverse education levels for version 3 of the Alzheimer's Disease Centers’ neuropsychological test battery in the Uniform Data Set

IF 11.1 1区医学 Q1 CLINICAL NEUROLOGY

Alzheimer's & Dementia Pub Date : 2025-09-23 DOI:10.1002/alz.70671

Gregory Brown, Diego Bustamante-Paytan, María Fe Albujar Pereira, Jose Huilca, Belén Custodio, Katherine Agüero, Graciet Verastegui, Zadith Yauri, Pamela Bartolo, Daniela Bendezu, Rosa Montesinos, Nilton Custodio

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引用次数: 0

Abstract

INTRODUCTION

Demographically adjusted norms are essential for interpreting cognitive tests, yet none exist in Peru for the Alzheimer's Disease Centers’ (ADCs) neuropsychological test battery, especially among low-education populations.

METHODS

We assessed 340 healthy adults (ages 43–79, 70% female), balanced by education level (0–6 years, n = 173; ≥ 7 years, n = 167). Participants completed the Uniform Data Set version 3 Neuropsychological Battery (UDS3-NB). Normative values were generated using linear regression with age, education, and sex as predictors.

RESULTS

Education groups were matched for age (p = 0.970) and sex (p = 0.904). Neuropsychological measurements varied significantly between education groups, with education emerging as the primary influential factor across all measures, except semantic fluency: vegetables.

DISCUSSION

This study provides comprehensive normative cognitive data for Peruvian adults across a range of education levels, which will assist in the more precise identification of cognitive impairments. Clinicians can determine individual z scores for each neuropsychological measure with the included calculator.

Highlights

We developed demographically adjusted normative data and a z score calculator for the Uniform Data Set version 3 Neuropsychological Battery among Peruvian adults.
Recruitment was balanced by education level (0–6 vs. ≥ 7 years) to reflect the diverse educational backgrounds in Peru.
Education was the strongest predictor of performance across most cognitive tests, particularly for working memory/executive tasks.
These normative data support more accurate cognitive assessments and dementia diagnoses in Peruvian populations.

Abstract Image

查看原文本刊更多论文

在统一数据集中，针对阿尔茨海默病中心神经心理测试单元版本3的不同教育水平秘鲁人的人口统计学调整的规范数据

人口统计学调整的规范对于解释认知测试至关重要，但秘鲁没有针对阿尔茨海默病中心（adc）神经心理学测试的规范，特别是在低教育水平人群中。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Alzheimer's & Dementia 医学-临床神经学

CiteScore

14.50

自引率

5.00%

发文量

299

审稿时长

3 months

期刊介绍： Alzheimer's & Dementia is a peer-reviewed journal that aims to bridge knowledge gaps in dementia research by covering the entire spectrum, from basic science to clinical trials to social and behavioral investigations. It provides a platform for rapid communication of new findings and ideas, optimal translation of research into practical applications, increasing knowledge across diverse disciplines for early detection, diagnosis, and intervention, and identifying promising new research directions. In July 2008, Alzheimer's & Dementia was accepted for indexing by MEDLINE, recognizing its scientific merit and contribution to Alzheimer's research.