Advances in FRET methodologies for probing molecular interactions.

IF 3.1 3区生物学 Q2 BIOPHYSICS

Biophysical journal Pub Date : 2025-09-22 DOI:10.1016/j.bpj.2025.08.027

Geetika Verma,Vasanthi Jayaraman

引用次数: 0

Abstract

Förster resonance energy transfer (FRET) has evolved into a powerful, quantitative approach for probing biomolecular structure, dynamics, and interactions. This research highlight brings together recent studies in Biophysical Journal that push the boundaries of traditional FRET. These innovations expand the spatial and temporal resolution of FRET, enabling its application to increasingly complex biological systems.

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用于探测分子相互作用的FRET方法的进展。

Förster共振能量转移（FRET）已经发展成为一个强大的，定量的方法来探测生物分子结构，动力学和相互作用。这项研究重点汇集了最近在生物物理杂志上的研究，突破了传统FRET的界限。这些创新扩大了FRET的空间和时间分辨率，使其应用于日益复杂的生物系统。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biophysical journal 生物-生物物理

CiteScore

6.10

自引率

5.90%

发文量

3090

审稿时长

2 months

期刊介绍： BJ publishes original articles, letters, and perspectives on important problems in modern biophysics. The papers should be written so as to be of interest to a broad community of biophysicists. BJ welcomes experimental studies that employ quantitative physical approaches for the study of biological systems, including or spanning scales from molecule to whole organism. Experimental studies of a purely descriptive or phenomenological nature, with no theoretical or mechanistic underpinning, are not appropriate for publication in BJ. Theoretical studies should offer new insights into the understanding ofexperimental results or suggest new experimentally testable hypotheses. Articles reporting significant methodological or technological advances, which have potential to open new areas of biophysical investigation, are also suitable for publication in BJ. Papers describing improvements in accuracy or speed of existing methods or extra detail within methods described previously are not suitable for BJ.