Heat-related mortality in Europe during 2024 and health emergency forecasting to reduce preventable deaths.

IF 50 1区 医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY
Tomáš Janoš, Marcos Quijal-Zamorano, Natalia Shartova, Elisa Gallo, Raúl Fernando Méndez Turrubiates, Nadia Denisse Beltrán Barrón, Fabien Peyrusse, Joan Ballester
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引用次数: 0

Abstract

Successive record-breaking summer temperatures, both globally and in Europe, raise the urgent question of how to better protect vulnerable populations. Here we quantified the heat-related mortality burden during the summers of 2022-2024, and assessed the forecast skill of a new generation of continental-wide, impact-based early warning systems during health emergencies. We fitted epidemiological models with the newly created, format-homogeneous daily mortality database of the EARLY-ADAPT project, covering 654 contiguous regions across 32 European countries, which represents the entire urban and rural population of 539 million people. We estimated 62,775 (95% confidence interval = 36,765-84,379) heat-related deaths in 2024, largely exceeding the burden in 2023 (50,798; 29,442-68,610), but somewhat smaller than that of 2022 (67,873; 38,465-92,455). We demonstrated that health emergencies can be forecast with high confidence at least 1 week in advance, even for highly vulnerable regions and population subgroups. These findings have implications for public health agencies and end users, given that the adoption of the system would enable reliable heat-health emergency alerts within the time window that is relevant for stakeholders to take effective actions to reduce preventable deaths.

2024年欧洲与热有关的死亡率和卫生紧急预报,以减少可预防的死亡。
全球和欧洲连续破纪录的夏季气温,提出了如何更好地保护弱势群体的紧迫问题。在这里,我们量化了2022-2024年夏季与热相关的死亡负担,并评估了新一代全大陆基于影响的突发卫生事件预警系统的预测技能。我们将流行病学模型与EARLY-ADAPT项目新创建的格式相同的每日死亡率数据库进行了拟合,该数据库覆盖了32个欧洲国家的654个连续地区,代表了5.39亿城市和农村人口。我们估计2024年与热相关的死亡人数为62,775人(95%置信区间= 36,765-84,379),大大超过2023年的负担(50,798;29,442-68,610),但略低于2022年的负担(67,873;38,465-92,455)。我们证明,即使是在高度脆弱的地区和人口亚群体,至少提前一周也可以高可信度地预测突发卫生事件。这些发现对公共卫生机构和最终用户具有启示意义,因为采用该系统将在时间窗口内实现可靠的热健康紧急警报,这与利益相关者采取有效行动减少可预防的死亡有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Nature Medicine
Nature Medicine 医学-生化与分子生物学
CiteScore
100.90
自引率
0.70%
发文量
525
审稿时长
1 months
期刊介绍: Nature Medicine is a monthly journal publishing original peer-reviewed research in all areas of medicine. The publication focuses on originality, timeliness, interdisciplinary interest, and the impact on improving human health. In addition to research articles, Nature Medicine also publishes commissioned content such as News, Reviews, and Perspectives. This content aims to provide context for the latest advances in translational and clinical research, reaching a wide audience of M.D. and Ph.D. readers. All editorial decisions for the journal are made by a team of full-time professional editors. Nature Medicine consider all types of clinical research, including: -Case-reports and small case series -Clinical trials, whether phase 1, 2, 3 or 4 -Observational studies -Meta-analyses -Biomarker studies -Public and global health studies Nature Medicine is also committed to facilitating communication between translational and clinical researchers. As such, we consider “hybrid” studies with preclinical and translational findings reported alongside data from clinical studies.
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