Cyanostyryl-Guanidiniocarbonyl-Pyrrole Amphiphiles: From Aggregation-Induced Emission to Photodimerization, Self-Assembly, and Bioimaging.

IF 2.8 4区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

ChemPlusChem Pub Date : 2025-09-23 DOI:10.1002/cplu.202500542

Kevin Rudolph, Lea Höfmann, Sidharth Thulaseedharan Nair Sailaja, Alexander Höing, Johannes Koch, Nina Schulze, Elisabeth Verheggen, Felix C Niemeyer, Florian Uteschil, Shirley K Knauer, Jens Voskuhl

引用次数: 0

Abstract

Two Cyanostyryl-guanidiniocarbonyl-pyrrole based amphiphiles are synthesized and examined in detail. In addition to achieving aggregation-induced emission from self-assembly, resulting in nanoparticles, it was found that the observed [2 + 2] photocycloaddition tunes the photophysical properties. The guanidiniocarbonyl-pyrrole component of these hybrid luminophores is shown to bind oxo-anions, such as pyrene-tetracarboxylate, as confirmed by fluorescence lifetime measurements. Moreover, both amphiphiles are used in bio-imaging experiments with HeLa cells, demonstrating effective cellular uptake.

查看原文本刊更多论文

氰苯基-胍基羰基-吡咯两亲体：从聚集诱导发射到光二聚化、自组装和生物成像。

合成了两种氰基苯基胍基羰基吡咯基两亲化合物，并对其进行了详细的研究。除了实现自组装引起的聚集诱导发射，产生纳米颗粒外，还发现观察到的[2 + 2]光环加成调节了光物理性质。通过荧光寿命测量证实，这些杂化发光团的胍基羰基吡咯成分可以结合氧阴离子，如芘四羧酸盐。此外，这两种两亲动物都被用于HeLa细胞的生物成像实验，显示出有效的细胞摄取。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

ChemPlusChem CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

5.90

自引率

0.00%

发文量

200

审稿时长

1 months

期刊介绍： ChemPlusChem is a peer-reviewed, general chemistry journal that brings readers the very best in multidisciplinary research centering on chemistry. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies. Fully comprehensive in its scope, ChemPlusChem publishes articles covering new results from at least two different aspects (subfields) of chemistry or one of chemistry and one of another scientific discipline (one chemistry topic plus another one, hence the title ChemPlusChem). All suitable submissions undergo balanced peer review by experts in the field to ensure the highest quality, originality, relevance, significance, and validity.