{"title":"The CL1 as a platform technology to leverage biological neural system functions","authors":"Brett J. Kagan","doi":"10.1038/s44222-025-00340-3","DOIUrl":null,"url":null,"abstract":"The CL1 is a scalable device for interacting with in vitro neural cell cultures via electrical activity in a closed-loop real-time environment coupled with an integrated life-support perfusion circuit. Here we explore the key component that constitutes the CL1 along with the various opportunities this platform technology can address.","PeriodicalId":74248,"journal":{"name":"Nature reviews bioengineering","volume":"3 9","pages":"724-725"},"PeriodicalIF":37.6000,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature reviews bioengineering","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s44222-025-00340-3","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The CL1 is a scalable device for interacting with in vitro neural cell cultures via electrical activity in a closed-loop real-time environment coupled with an integrated life-support perfusion circuit. Here we explore the key component that constitutes the CL1 along with the various opportunities this platform technology can address.