Magnetic and luminescence properties of bioactive glass nanoparticles for biomedical applications

IF 2.1 4区材料科学 Q2 MATERIALS SCIENCE, CERAMICS

Journal of the Australian Ceramic Society Pub Date : 2024-12-30 DOI:10.1007/s41779-024-01141-4

Fatma Unal, Batur Ercan

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Abstract

This study explores the synthesis and characterization of superparamagnetic iron oxide nanoparticles (SPIONs) coated with zinc (Zn) and/or europium (Eu) doped bioactive glass. Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM) confirmed spherical agglomerated morphology and core@shell structure, respectively. High-Resolution TEM (HR-TEM) revealed lattice fringe values consistent with the cubic magnetite phase. Magnetic property assessment showed stable superparamagnetic behavior with slight reductions in saturation magnetization (σ_s) after immersion in simulated body fluid (SBF) solution. Photoluminescence (PL) spectra of Eu-doped samples exhibited red emission, confirming Eu rare earth element incorporation and maintaining luminescence post-immersion in SBF. Upon the interaction with SBF, hydroxyapatite (HA) formation occurred on the nanoparticle surfaces, suggesting the bioactive nature of the nanoparticles. These findings suggest that the synthesized nanoparticles exhibit promising potential for biomedical applications, including imaging, and orthopedics, due to their bioactive, magnetic, and luminescent properties.

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生物医学应用中生物活性玻璃纳米颗粒的磁性和发光特性

本研究探讨了超顺磁性氧化铁纳米粒子（SPIONs）的合成和表征，SPIONs包覆有锌（Zn）和/或铕（Eu）掺杂的生物活性玻璃。扫描电子显微镜（SEM）和透射电子显微镜（TEM）分别证实了球团形态和core@shell结构。高分辨率透射电镜（HR-TEM）显示晶格条纹值与立方磁铁矿相一致。磁性能评价表明，在模拟体液（SBF）溶液中浸泡后，饱和磁化强度（σs）略有降低，超顺磁性行为稳定。Eu掺杂样品的光致发光（PL）光谱显示出红色发射，证实了Eu稀土元素的掺入，并在SBF中浸没后保持发光。与SBF相互作用后，纳米颗粒表面形成羟基磷灰石（HA），表明纳米颗粒具有生物活性。这些发现表明，由于其生物活性、磁性和发光特性，合成的纳米颗粒在生物医学应用方面具有很大的潜力，包括成像和骨科。

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来源期刊

Journal of the Australian Ceramic Society Materials Science-Materials Chemistry

CiteScore

3.70

自引率

5.30%

发文量

123

期刊介绍： Publishes high quality research and technical papers in all areas of ceramic and related materials Spans the broad and growing fields of ceramic technology, material science and bioceramics Chronicles new advances in ceramic materials, manufacturing processes and applications Journal of the Australian Ceramic Society since 1965 Professional language editing service is available through our affiliates Nature Research Editing Service and American Journal Experts at the author''s cost and does not guarantee that the manuscript will be reviewed or accepted