Separation and purification of PNS from Sanqi extract by a rosin-based polymer microsphere

IF 2.3 4区化学 Q3 CHEMISTRY, PHYSICAL

Colloid and Polymer Science Pub Date : 2025-06-19 DOI:10.1007/s00396-025-05458-9

Zhenfang Zeng, Wei Wei, Wen Li, Hao Li, Mengling Wei, Zheng He, Wenkun Huang, Fuhou Lei

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引用次数: 0

Abstract

Panax notoginseng saponins (PNS) is a natural medicine known for its ability to promote blood circulation, remove blood stasis, reduce swelling, and relieve pain. However, obtaining high-purity PNS from the crude extract of the medicinal plant Sanqi is a challenging and important task. In this study, a novel rosin-based diatomite polymer microsphere (RDPMs) was synthesized, and its physical and chemical properties were characterized using various analytical techniques. The adsorption capacity of RDPMs for PNS was 273.69 mg·g⁻¹, with an increase in PNS content from 44.38 to 79.59%. The process was spontaneous, endothermic, and multilayered, controlled by physical and chemical factors. Quantum chemical calculations revealed that there are van der Waals forces, H-bonding, and electrostatic interactions between RDPMs and PNS. Overall, RDPMs is an effective and reusable bioadsorbent with potential for isolating PNS from Sanqi extract.

Graphical Abstract

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松香基聚合物微球分离纯化三七提取物中PNS

三七皂苷（PNS）是一种天然药物，以其促进血液循环、祛瘀、消肿和缓解疼痛的能力而闻名。然而，从药用植物三七粗提物中提取高纯度PNS是一项具有挑战性和重要的任务。本研究合成了一种新型的松香基硅藻土聚合物微球（RDPMs），并利用各种分析技术对其理化性质进行了表征。rdms对PNS的吸附量为273.69 mg·g−1，PNS的含量从44.38%增加到79.59%。该过程是自发的、吸热的、多层的、受物理和化学因素控制的过程。量子化学计算表明，rdpm和PNS之间存在范德华力、氢键和静电相互作用。综上所述，rdpm是一种有效的可重复利用的生物吸附剂，具有从三七提取物中分离PNS的潜力。图形抽象

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Colloid and Polymer Science 化学-高分子科学

CiteScore

4.60

自引率

4.20%

发文量

111

审稿时长

2.2 months

期刊介绍： Colloid and Polymer Science - a leading international journal of longstanding tradition - is devoted to colloid and polymer science and its interdisciplinary interactions. As such, it responds to a demand which has lost none of its actuality as revealed in the trends of contemporary materials science.