Solitary fibrous tumor of the prostate: Case report and literature review

Abstract

Solitary fibrous tumor (SFT) of the prostate is a rare mesenchymal neoplasm with only a few cases reported. Its clinical presentation often mimics benign prostatic hyperplasia, and imaging findings are nonspecific. Diagnosis relies on histopathology and immunohistochemistry, particularly STAT6 nuclear expression. Most cases follow a benign course, but some may exhibit aggressive behavior. Complete surgical resection with clear margins is the treatment of choice, with no established role for adjuvant therapy. This report discusses a case of prostatic SFT, emphasizing its diagnostic challenges, imaging findings, and surgical management, contributing to the limited literature on this rare entity.