Mycobacterium chimaera choroidal granuloma: A case report and review of the literature

Q3 Medicine

American Journal of Ophthalmology Case Reports Pub Date : 2025-09-01 DOI:10.1016/j.ajoc.2025.102422

Matthew Pfannenstiel , Mackenzie Penny , Maram El-Geneidy , Idaima Calderon , Rachel Weihe , Radwan S. Ajlan

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引用次数: 0

Abstract

Purpose

To report a case of a patient that developed a choroidal granulomatous lesion secondary to disseminated Mycobacterium chimaera (MC) infection that was successfully treated with systemic and ocular steroids.

Observations

A 60-year-old male with a history of multiple cardiothoracic surgeries complicated by disseminated MC was referred to retina clinic. On initial examination, bilateral choroidal lesions were noted consistent with MC choroiditis. These lesions were treated with systemic antimicrobials. Five months later, the patient was found to have a new choroidal lesion in his right eye concerning for a choroidal granuloma. Optical coherence tomography showed an elevated choroidal lesion with subretinal fluid. The granulomatous choroidal lesion regressed after starting systemic and local steroids. There was no recurrence of the granulomatous choroidal lesion at the most recent follow up visit.

Conclusions and Importance

This is an extremely rare report of a patient who received successful treatment for a MC related choroidal granulomatous lesion with accompanying multimodal imaging. The report suggests that similar lesions can be treated with systemic and ocular steroid therapy in combination with systemic antimicrobials.

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嵌合分枝杆菌脉络膜肉芽肿1例报告及文献复习

目的报告一例播散性嵌合分枝杆菌（MC）感染继发脉络膜肉芽肿病变，经全身和眼部类固醇治疗成功的病例。观察一位60岁男性，多次心胸外科手术合并弥散性MC被转介到视网膜诊所。在初步检查中，双侧脉络膜病变与MC脉络膜炎一致。这些病变用全身抗菌剂治疗。5个月后，患者发现右眼有新的脉络膜病变，可能是脉络膜肉芽肿。光学相干断层扫描显示脉络膜病变升高伴视网膜下积液。在开始全身和局部类固醇治疗后，肉芽肿性脉络膜病变消退。在最近的随访中，没有肉芽肿性脉络膜病变复发。结论和重要性：这是一个极为罕见的病例，患者接受了MC相关脉络膜肉芽肿病变的成功治疗，并伴有多模态成像。该报告建议，类似的病变可以用全身和眼部类固醇治疗联合全身抗菌剂治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American Journal of Ophthalmology Case Reports Medicine-Ophthalmology

CiteScore

2.40

自引率

0.00%

发文量

513

审稿时长

16 weeks

期刊介绍： The American Journal of Ophthalmology Case Reports is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished case report manuscripts directed to ophthalmologists and visual science specialists. The cases shall be challenging and stimulating but shall also be presented in an educational format to engage the readers as if they are working alongside with the caring clinician scientists to manage the patients. Submissions shall be clear, concise, and well-documented reports. Brief reports and case series submissions on specific themes are also very welcome.