High efficient synthesis of HMX from DPT using deep eutectic catalyst

IF 2.2 3区化学 Q2 CHEMISTRY, ORGANIC

Tetrahedron Pub Date : 2025-09-16 DOI:10.1016/j.tet.2025.134936

Jianjian Hu , Dapeng Jiang , Yujie Huang , Xixue Liu , Shenyuan Gao , Kejun Wu , Chaohong He , Liyan Dai

引用次数: 0

Abstract

A deep eutectic catalyst (DEC) catalyzed nitration reaction for synthesizing 1,3,5,7-tetranitro-1,3,5,7-tetrazocane (HMX) from 3,7-dinitro-1,3,5,7-tetraazabicyclo[3,3,1]nonane (DPT) has been developed, using a reduced amount of fuming nitric acid and achieving a maximum yield of 85.8 %. In addition, the introduction of DEC significantly enhanced the nitration efficiency of nitrogen-containing substrates such as dimorpholinomethane and dipiperidinomethane, notably increasing the yields of their corresponding nitroso products. This method provides a greener and more economical alternative to ionic liquid-based processes.

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用深共晶催化剂从DPT高效合成HMX

以3,7-二硝基-1,3,5,7-四氮杂环[3,3,3,1]壬烷（DPT）为原料，采用深共晶催化剂（DEC）催化硝化反应合成1,3,5,7-四硝基-1,3,5,7-四氮杂烷（HMX），减少了发烟硝酸的用量，收率最高可达85.8%。此外，DEC的引入显著提高了含氮底物如二morpholinmethane和dipiperidinmethane的硝化效率，显著提高了相应亚硝基产物的产率。这种方法为基于离子液体的工艺提供了一种更环保、更经济的替代方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Tetrahedron 化学-有机化学

CiteScore

3.90

自引率

4.80%

发文量

439

审稿时长

34 days

期刊介绍： Tetrahedron publishes full accounts of research having outstanding significance in the broad field of organic chemistry and its related disciplines, such as organic materials and bio-organic chemistry. Regular papers in Tetrahedron are expected to represent detailed accounts of an original study having substantially greater scope and details than that found in a communication, as published in Tetrahedron Letters. Tetrahedron also publishes thematic collections of papers as special issues and ''Reports'', commissioned in-depth reviews providing a comprehensive overview of a research area.