Advances in physical and chemical strategies for dentin hypersensitivity therapy

IF 13 1区 综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES
Xinru Li, Qihui Wang, Yirong Sun, Guoliang Wang, Congxiao Zhang, Jianxun Ding
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引用次数: 0

Abstract

Background

Dentin hypersensitivity (DH) is a prevalent and acute dental pain disorder marked by a brief yet sharp toothache caused by exposed dentin, often in response to thermal, chemical, and mechanical stimuli. It significantly affects a person’s quality of life, interfering with routine activities, such as eating and drinking. With an improved understanding of the mechanisms underlying DH, various physical and chemical strategies have been developed to alleviate the condition.

Aim of the review

This review evaluates three principal mechanistic theories underlying DH desensitization, including the Direct Innervation Hypothesis, the Odontoblast Receptor Theory, and the Hydrodynamic Theory. It provides a detailed analysis of current physical, chemical, and synergistic therapeutic methods used for desensitization. Additionally, it discusses potential future therapeutic approaches for the treatment of DH.

Key scientific concepts of review

This review highlights recent advancements and ongoing challenges in applying physical and chemical strategies for DH treatment. It also discusses potential future strategies and methods, offering insights into the prospects for the field.

Abstract Image

牙本质过敏的理化治疗策略研究进展
牙本质过敏(DH)是一种常见的急性牙痛疾病,其特征是牙本质暴露引起的短暂而尖锐的牙痛,通常是对热、化学和机械刺激的反应。它会严重影响一个人的生活质量,干扰日常活动,如饮食。随着对DH机制的进一步了解,各种物理和化学策略已经被开发出来以缓解这种情况。本文综述了三种主要的脱敏机制理论,包括直接神经支配理论、成牙髓细胞受体理论和流体动力学理论。它详细分析了目前用于脱敏的物理、化学和协同治疗方法。此外,它还讨论了治疗DH的潜在未来治疗方法。本综述重点介绍了应用物理和化学策略治疗DH的最新进展和面临的挑战。它还讨论了潜在的未来战略和方法,为该领域的前景提供了见解。
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来源期刊
Journal of Advanced Research
Journal of Advanced Research Multidisciplinary-Multidisciplinary
CiteScore
21.60
自引率
0.90%
发文量
280
审稿时长
12 weeks
期刊介绍: Journal of Advanced Research (J. Adv. Res.) is an applied/natural sciences, peer-reviewed journal that focuses on interdisciplinary research. The journal aims to contribute to applied research and knowledge worldwide through the publication of original and high-quality research articles in the fields of Medicine, Pharmaceutical Sciences, Dentistry, Physical Therapy, Veterinary Medicine, and Basic and Biological Sciences. The following abstracting and indexing services cover the Journal of Advanced Research: PubMed/Medline, Essential Science Indicators, Web of Science, Scopus, PubMed Central, PubMed, Science Citation Index Expanded, Directory of Open Access Journals (DOAJ), and INSPEC.
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