Jeffrey C. Jones, Omar G. García, Julian A. Villalba, Rosa Hinojosa, Marissa L. Taylor, Pallavi Annambhotla, Matthias H. Kapturczak, Bonny Mayes, Sandor E. Karpathy, Arlyn N. Gleaton, Linda Moon, Joseph Singleton, Sridhar V. Basavaraju, Christopher D. Paddock
{"title":"Organ Donor Transmission of Rickettsia typhi to Kidney Transplant Recipients, Texas, USA, 2024","authors":"Jeffrey C. Jones, Omar G. García, Julian A. Villalba, Rosa Hinojosa, Marissa L. Taylor, Pallavi Annambhotla, Matthias H. Kapturczak, Bonny Mayes, Sandor E. Karpathy, Arlyn N. Gleaton, Linda Moon, Joseph Singleton, Sridhar V. Basavaraju, Christopher D. Paddock","doi":"10.3201/eid3110.250961","DOIUrl":null,"url":null,"abstract":"<p>Murine typhus, a fleaborne disease caused by the bacterium <em>Rickettsia typhi,</em> is found throughout temperate and tropical regions of the world. Transmission of <em>R. typhi</em> to humans involves several species of fleas, and most infections result from direct inoculation of <em>R. typhi</em>–infected flea feces into abrasions in the skin. We describe the transmission of <em>R. typhi</em> from an organ donor in Texas, USA, to 2 kidney transplant recipients. The donor and 1 recipient died from the infection. The occurrence of <em>R. typhi</em> transmission is a harbinger for the reemergence of murine typhus in some of the most densely populated metropolitan areas of the United States. Our findings reinforce the need to improve healthcare provider and public awareness of this life-threatening but treatable infection.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"35 1","pages":""},"PeriodicalIF":6.6000,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Emerging Infectious Diseases","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3201/eid3110.250961","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Murine typhus, a fleaborne disease caused by the bacterium Rickettsia typhi, is found throughout temperate and tropical regions of the world. Transmission of R. typhi to humans involves several species of fleas, and most infections result from direct inoculation of R. typhi–infected flea feces into abrasions in the skin. We describe the transmission of R. typhi from an organ donor in Texas, USA, to 2 kidney transplant recipients. The donor and 1 recipient died from the infection. The occurrence of R. typhi transmission is a harbinger for the reemergence of murine typhus in some of the most densely populated metropolitan areas of the United States. Our findings reinforce the need to improve healthcare provider and public awareness of this life-threatening but treatable infection.
期刊介绍：
Emerging Infectious Diseases is a monthly open access journal published by the Centers for Disease Control and Prevention. The primary goal of this peer-reviewed journal is to advance the global recognition of both new and reemerging infectious diseases, while also enhancing our understanding of the underlying factors that contribute to disease emergence, prevention, and elimination.
Targeted towards professionals in the field of infectious diseases and related sciences, the journal encourages diverse contributions from experts in academic research, industry, clinical practice, public health, as well as specialists in economics, social sciences, and other relevant disciplines. By fostering a collaborative approach, Emerging Infectious Diseases aims to facilitate interdisciplinary dialogue and address the multifaceted challenges posed by infectious diseases.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
