Short-term survivorship of antioxidant highly cross-linked polyethylene liners in total hip arthroplasty reported in American Joint Replacement Registry.

IF 2.3 Q2 ORTHOPEDICS
Kirstin Jones, Amber M Muehlmann, Sarah M Melvin, Ebru Oral, Colin T Penrose
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引用次数: 0

Abstract

Background: Total hip arthroplasty is a safe and effective procedure. To improve survivorship, ultrahigh molecular weight polyethylene hip liners with antioxidants have been developed. Additive antioxidant was deployed to reduce oxidation and consequential wear, loosening, or osteolysis. A unique manufacturing process was utilized for two such hip liners, the Novation® and Alteon® XLE hip liners and this research represents the first large series on this specific material. The study hypothesis was that Novation and Alteon XLE hip liners have similar short-term survivorship as other manufacturers' antioxidant liners according to procedure and outcome data from the American Joint Replacement Registry (AJRR).

Aim: To demonstrate similar short-term survivorship of XLE antioxidant hip liners compared to all antioxidant hip liners in AJRR.

Methods: Utilizing total hip arthroplasty data from the AJRR, a retrospective review was performed for subjects who underwent implantation of Novation XLE (n = 461), Alteon XLE (n = 989), or any other antioxidant hip liner (termed the aggregate antioxidant group; n = 39964) as of March 31, 2022. Survivorship at three years and revision rates were compared statistically between the Novation group and the aggregate antioxidant group as well as the Alteon group and the aggregate antioxidant group.

Results: Survivorship at three years post-surgery was 99.09% for Novation, 97.73% for Alteon, and 97.69% for the aggregate antioxidant group. There were no reports of failure due to wear in either the Novation or Alteon groups. Among the revision categories (fracture, infection, aseptic loosening, instability, mechanical complications, wear, pain, hematoma/wound complications, or other), there were no significant differences identified in either comparison. There were also no significant differences in cumulative percent revision rates up to three years post-surgery for the Novation vs aggregate antioxidant group or the Alteon vs aggregate antioxidant group.

Conclusion: Novation and Alteon XLE hip liner revision rate and survivorship are equivalent to other antioxidant hip liners in the short term.

Abstract Image

美国关节置换注册中心报道了抗氧化高交联聚乙烯衬垫在全髋关节置换术中的短期存活。
背景:全髋关节置换术是一种安全有效的手术。为了提高生存率,研究人员开发了抗氧化剂超高分子量聚乙烯髋关节衬垫。添加抗氧化剂以减少氧化和随之而来的磨损、松动或骨溶解。两种髋关节衬垫采用了独特的制造工艺,Novation®和Alteon®XLE髋关节衬垫,这项研究代表了这种特定材料的第一个大型系列。根据美国关节置换登记(AJRR)的程序和结果数据,研究假设Novation和Alteon XLE髋关节衬垫与其他制造商的抗氧化衬垫具有相似的短期生存期。目的:在AJRR中,与所有抗氧化髋关节衬垫相比,证明XLE抗氧化髋关节衬垫的短期生存率相似。方法:利用AJRR的全髋关节置换术数据,对截至2022年3月31日接受Novation XLE (n = 461)、Alteon XLE (n = 989)或任何其他抗氧化髋关节衬垫(称为总抗氧化组;n = 39964)植入的受试者进行回顾性研究。对Novation组和综合抗氧化组、Alteon组和综合抗氧化组的3年生存率和修正率进行统计学比较。结果:Novation组术后3年生存率为99.09%,Alteon组为97.73%,综合抗氧化剂组为97.69%。Novation组和Alteon组都没有因磨损而导致的故障报告。在翻修类别(骨折、感染、无菌性松动、不稳定、机械并发症、磨损、疼痛、血肿/伤口并发症或其他)中,两种比较均未发现显著差异。Novation组与聚合抗氧化剂组或Alteon组与聚合抗氧化剂组术后3年的累计翻修率也无显著差异。结论:Novation和Alteon XLE髋关节衬垫翻修率和生存率在短期内与其他抗氧化髋关节衬垫相当。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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