{"title":"Metastatic Mediastinal Germ Cell Tumour: A Florid and Fulminant Presentation.","authors":"Zhong Xhen Khor","doi":"10.1002/rcr2.70348","DOIUrl":null,"url":null,"abstract":"<p><p>A previously healthy teenager presented with acute respiratory distress and constitutional symptoms. Imaging revealed a mediastinal mass with multiple pulmonary nodules, and markedly elevated β-HCG confirmed metastatic choriocarcinoma. Despite urgent chemotherapy, he succumbed within a week. This case underscores its rarity, diagnostic challenge, and dismal prognosis in tuberculosis-endemic regions.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 9","pages":"e70348"},"PeriodicalIF":0.8000,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12444773/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Respirology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/rcr2.70348","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/9/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}
引用次数: 0
Abstract
A previously healthy teenager presented with acute respiratory distress and constitutional symptoms. Imaging revealed a mediastinal mass with multiple pulmonary nodules, and markedly elevated β-HCG confirmed metastatic choriocarcinoma. Despite urgent chemotherapy, he succumbed within a week. This case underscores its rarity, diagnostic challenge, and dismal prognosis in tuberculosis-endemic regions.
期刊介绍:
Respirology Case Reports is an open-access online journal dedicated to the publication of original clinical case reports, case series, clinical images and clinical videos in all fields of respiratory medicine. The Journal encourages the international exchange between clinicians and researchers of experiences in diagnosing and treating uncommon diseases or diseases with unusual presentations. All manuscripts are peer-reviewed through a streamlined process that aims at providing a rapid turnaround time from submission to publication.