Evaluating a non-pharmacological treatment for primary premature ejaculation patients with low sexual frequency: a retrospective study on vacuum negative pressure hydropneumatic/pneumatic bubble massage.

IF 2 3区医学 Q1 MEDICINE, GENERAL & INTERNAL

Sexual Medicine Pub Date : 2025-09-16 eCollection Date: 2025-08-01 DOI:10.1093/sexmed/qfaf069

Qing-Qiang Gao, Chao-Ba He, Bin Wang, Yu-Tian Dai, Bai-Bing Yang, Xiao-Zhi Zhao

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引用次数: 0

Abstract

Background: Premature ejaculation (PE) is a common male sexual dysfunction with treatment limitations including side effects and partner dependency.

Aim: To evaluate vacuum negative pressure hydropneumatic/pneumatic bubble massage (VNPHP/PBM) efficacy in primary PE (PPE) patients stratified by sexual frequency, focusing on subjective low-frequency (avoidance due to PE) vs objective low-frequency subgroups.

Methods: Retrospective analysis of 42 PPE patients: 22 low-frequency (LF; <4 intercourse/month) including 13 subjective (sub-LF) and 9 objective (ob-LF) vs 20 non-low-frequency (NLF; ≥4/month).

Outcomes: Primary: intravaginal ejaculation latency time (IELT); secondary: Premature Ejaculation Diagnostic Tool (PEDT), Self-Rating Anxiety Scale (SAS) scores, and sexual frequency changes at 4 weeks.

Results: Both groups showed significant improvements in IELT, PEDT, and SAS scores (P < .05). Low-frequency group showed greater improvements than NLF in PEDT reduction (6.36 ± 2.38 vs 7.90 ± 2.02, P = .03), SAS reduction (30.95 ± 9.57 vs 38.45 ± 8.85, P = .01), and sexual frequency increase (0.50 [0.00, 4.00] vs 1.00 [1.00, 2.00], P = .02). Crucially, sub-LF patients exhibited dramatic sexual frequency normalization (6.00 [4.00, 7.50] vs 2.00 [1.00, 2.00], P < .001), while ob-LF unchanged (P = .56). No adverse events.

Clinical implications: Vacuum negative pressure hydropneumatic/pneumatic bubble massage is a partner-independent therapy that not only improves ejaculatory control but also restores sexual activity in patients avoiding intercourse due to PE-related anxiety.

Strengths and limitations: Strengths: First study analyzing subjective vs objective low-frequency PE, standardized protocols. Limitations: Retrospective design, self-reported IELT data, lack of a control group, and the non-blinded nature of the study.

Conclusion: Vacuum negative pressure hydropneumatic/pneumatic bubble massage significantly improves PE symptoms with amplified benefits in low-frequency patients, particularly those with PE-driven sexual avoidance.

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评价性频率低的原发性早泄患者的非药物治疗：真空负压油气/气泡按摩的回顾性研究。

背景：早泄（PE）是一种常见的男性性功能障碍，其治疗存在副作用和伴侣依赖性等局限性。目的：评价真空负压油气/气泡按摩（VNPHP/PBM）在按性生活频率分层的原发性PE （PPE）患者中的疗效，重点关注主观低频（因PE而回避）与客观低频亚组。方法：回顾性分析42例PPE患者：22例低频（LF）；结果：主要：阴道内射精潜伏期（雅思）；其次：早泄诊断工具（PEDT），自评焦虑量表（SAS）评分，以及4周的性频率变化。结果：两组在雅思、PEDT、SAS评分上均有显著改善(P P =。03),减少SAS(30.95±9.57 vs 38.45±8.85,P =。性行为频率增加（0.50 [0.00,4.00]vs 1.00 [1.00, 2.00], P = 0.02）。至关重要的是，亚lf患者表现出戏剧性的性频率正常化（6.00 [4.00,7.50]vs 2.00 [1.00, 2.00], P P = 0.56）。无不良事件。临床意义：真空负压油气/气泡按摩是一种与伴侣无关的治疗方法，不仅可以改善射精控制，还可以恢复因pe相关焦虑而避免性交的患者的性活动。优势和局限性：优势：第一个研究分析主观与客观低频PE，标准化方案。局限性：回顾性设计，自我报告的雅思数据，缺乏对照组，以及研究的非盲性。结论：真空负压油气/气泡按摩可显著改善低频率PE患者的PE症状，尤其是PE驱动的性逃避患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Sexual Medicine MEDICINE, GENERAL & INTERNAL-

CiteScore

5.40

自引率

0.00%

发文量

103

审稿时长

22 weeks

期刊介绍： Sexual Medicine is an official publication of the International Society for Sexual Medicine, and serves the field as the peer-reviewed, open access journal for rapid dissemination of multidisciplinary clinical and basic research in all areas of global sexual medicine, and particularly acts as a venue for topics of regional or sub-specialty interest. The journal is focused on issues in clinical medicine and epidemiology but also publishes basic science papers with particular relevance to specific populations. Sexual Medicine offers clinicians and researchers a rapid route to publication and the opportunity to publish in a broadly distributed and highly visible global forum. The journal publishes high quality articles from all over the world and actively seeks submissions from countries with expanding sexual medicine communities. Sexual Medicine relies on the same expert panel of editors and reviewers as The Journal of Sexual Medicine and Sexual Medicine Reviews.