Maged Al-Najar, Baharudin Ibrahim, Ahsan Aftab Raja
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引用次数: 0
Abstract
Background: Breast cancer is the most common cancer among Yemeni women. In this study, we aimed to determine the socioeconomic and lifestyle factors of breast cancer risk and survival among Yemeni women in Thamar.
Objectives: We assessed the association between socioeconomic status, lifestyle factors, and the risk of developing breast cancer; and compared disease-free survival (DFS) and overall survival between urban and rural breast cancer patients.
Materials and methods: We performed a retrospective, case-control study using data from the Thamar cancer registry and household survey. Cases were women with histologically confirmed breast cancer diagnosed from January 1, 2019 to December 31, 2023, and frequency-matched controls included women without breast cancer. Risk determinants were determined using multivariate logistic regression models and survival outcomes were analyzed using Cox regression.
Results: A total of 115 cases and 119 controls were included in the study. Significant breast cancer-associated factors were illiteracy (adjusted odds ratio [aOR] =5.46, P < 0.001), wood fuel for cooking (aOR =15.8, P < 0.001), low monthly income below 200 USD (aOR =12.1, P < 0.001), and postmenopausal status (aOR =2.54, P = 0.035). The comparison of DFS between urban and rural residents showed no statistically significant difference.
Conclusions: The study identified illiteracy, wood fuel for cooking, postmenopausal status, and low monthly income as key associated factor for breast cancer among the cases and controls examined. No significant difference in DFS was observed between urban and rural residents.
背景：乳腺癌是也门妇女中最常见的癌症。在这项研究中，我们旨在确定塔马尔地区也门妇女乳腺癌风险和生存的社会经济和生活方式因素。目的：我们评估社会经济地位、生活方式因素与患乳腺癌风险之间的关系；并比较了城市和农村乳腺癌患者的无病生存率（DFS）和总生存率。材料和方法：我们使用来自Thamar癌症登记处和家庭调查的数据进行了回顾性病例对照研究。病例为2019年1月1日至2023年12月31日诊断的组织学证实的乳腺癌女性，频率匹配的对照组包括未患乳腺癌的女性。使用多变量logistic回归模型确定风险决定因素，并使用Cox回归分析生存结果。结果：共纳入115例病例和119例对照。与乳腺癌相关的显著因素为文盲（校正优势比[aOR] =5.46, P < 0.001）、做饭用的木柴（aOR =15.8, P < 0.001）、月收入低于200美元（aOR =12.1, P < 0.001）和绝经后状态（aOR =2.54, P = 0.035）。城乡居民DFS比较无统计学差异。结论：该研究发现，文盲、做饭用的木柴、绝经后状态和低月收入是被检查的病例和对照组中乳腺癌的关键相关因素。城乡居民的生活质量无显著差异。
期刊介绍：
Indian Journal of Public Health is a peer-reviewed international journal published Quarterly by the Indian Public Health Association. It is indexed / abstracted by the major international indexing systems like Index Medicus/MEDLINE, SCOPUS, PUBMED, etc. The journal allows free access (Open Access) to its contents and permits authors to self-archive final accepted version of the articles. The Indian Journal of Public Health publishes articles of authors from India and abroad with special emphasis on original research findings that are relevant for developing country perspectives including India. The journal considers publication of articles as original article, review article, special article, brief research article, CME / Education forum, commentary, letters to editor, case series reports, etc. The journal covers population based studies, impact assessment, monitoring and evaluation, systematic review, meta-analysis, clinic-social studies etc., related to any domain and discipline of public health, specially relevant to national priorities, including ethical and social issues. Articles aligned with national health issues and policy implications are prefered.
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