Ventricular Tachycardia Substrate Mapping with Cardiac Computed Tomography and Cardiac Magnetic Resonance Imaging: Head-to-head Comparison of Two Clinically Available Post-processing Platforms.

IF 5.7 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
Damian Laan, Luuk H G A Hopman, Rosa M Figueras I Ventura, Bruno Soré, Cornelis P Allaart, Michiel J B Kemme, Marco Götte, Pieter G Postema, Pranav Bhagirath
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引用次数: 0

Abstract

Background: Advanced postprocessing of late-gadolinium enhanced cardiac magnetic resonance (LGE-CMR) and computed tomography (CCT) imaging increasingly guides ventricular tachycardia (VT) ablation. However, a direct comparison between two widely adopted platforms, ADAS 3D LV (ADAS3D Medical) and inHEART (IHU LIRYC/Inria), is lacking.

Objective: To compare CMR- and CCT-derived ventricular substrate models generated by ADAS 3D and inHEART in patients with ischemic and non-ischemic cardiomyopathy undergoing VT ablation.

Methods: Patients who underwent both CCT and LGE-CMR prior to ablation were retrospectively included. ADAS 3D models were generated on-site, while inHEART models were processed remotely. Substrate models were evalauted using a custom scoring system incorporating quantitative (scar mass, transmurality) and qualitative (wall thickness, scar delineation, conduction corridors) parameters. Electroanatomical maps (EAM) assessed correspondence between low-voltage and ablation regions, with imaging-defined corridors.

Results: Sixteen patients (n=8 ischemic, n=8 non-ischemic) were analysed, 12 had detailed EAM data. Scar core and border zone measurements were comparable between platforms in both subgroups (all p>0.05). ADAS 3D showed slightly higher visualization scores, particularly in non-ischemic cardiomyopathy, though differences were not statistically significant. Spatial concordance between imaging-derived scar and EAM-defined ablation areas was good to excellent in 10 of 12 cases.

Conclusion: ADAS 3D and inHEART demonstrated high concordance in scar quantification and substrate characterization, with comparable performance across cardiomyopathy types. Given their complementary strengths, platform choice should be guided by procedural goals, imaging availability, operator experience, and institutional context, as each system offers distinct advantages. Prospective studies are needed to evaluate impact on procedural success and long-term outcomes.

用心脏计算机断层和心脏磁共振成像绘制室性心动过速底物:两种临床可用后处理平台的头对头比较。
背景:晚期钆增强心脏磁共振(LGE-CMR)和计算机断层扫描(CCT)成像的先进后处理越来越多地指导室性心动过速(VT)消融。然而,两种广泛采用的平台ADAS3D LV (ADAS3D Medical)和inHEART (IHU LIRYC/Inria)之间缺乏直接比较。目的:比较ADAS 3D和inHEART对缺血性和非缺血性心肌病行房室消融术患者CMR和cct衍生心室底物模型的影响。方法:回顾性纳入消融前同时接受CCT和LGE-CMR的患者。现场生成ADAS 3D模型,远程处理inHEART模型。使用自定义评分系统对基底模型进行评估,该评分系统包含定量(疤痕质量、跨壁性)和定性(壁厚、疤痕描绘、传导走廊)参数。电解剖图(EAM)通过成像确定的通道评估低压和消融区域之间的对应关系。结果:分析16例患者(缺血性8例,非缺血性8例),其中12例有详细的EAM数据。两个亚组平台间疤痕核心和边缘区的测量具有可比性(p < 0.05)。ADAS 3D显示出稍高的可视化评分,特别是在非缺血性心肌病中,尽管差异无统计学意义。12例中有10例影像学瘢痕与eam定义的消融区域的空间一致性良好至极好。结论:ADAS 3D和inHEART在疤痕量化和底物表征方面表现出高度一致性,在各种心肌病类型中表现相当。考虑到它们的互补优势,平台的选择应以程序目标、成像可用性、操作人员经验和机构背景为指导,因为每个系统都具有独特的优势。需要前瞻性研究来评估对手术成功和长期结果的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Heart rhythm
Heart rhythm 医学-心血管系统
CiteScore
10.50
自引率
5.50%
发文量
1465
审稿时长
24 days
期刊介绍: HeartRhythm, the official Journal of the Heart Rhythm Society and the Cardiac Electrophysiology Society, is a unique journal for fundamental discovery and clinical applicability. HeartRhythm integrates the entire cardiac electrophysiology (EP) community from basic and clinical academic researchers, private practitioners, engineers, allied professionals, industry, and trainees, all of whom are vital and interdependent members of our EP community. The Heart Rhythm Society is the international leader in science, education, and advocacy for cardiac arrhythmia professionals and patients, and the primary information resource on heart rhythm disorders. Its mission is to improve the care of patients by promoting research, education, and optimal health care policies and standards.
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