Anbuselvam Mohan, Katherine C Ji, Balasubramanian Chitra, Anbuselvam Jeeva, Hai-Feng Ji
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引用次数: 0
Abstract
Malaria is one of the major global public health problems, is primarily caused by protozoan parasites of the genus Plasmodium and transmitted through the bites of infected female Anopheles mosquitoes. N-Myristoyltransferase (NMT) is an important drug target, particularly for Plasmodium vivax. Therefore, it is of interest to describe the molecular docking analysis of N-myristoyl-transferase with small molecules from the ZINC database for screening potential anti-malarial drugs. Hence, we report four potential compounds namely ZINC37555319, ZINC41016284, ZINC41016205, and ZINC47160805 with acceptable ADME properties for further consideration.
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