Feline leukaemia virus subgrouping using a viral interference assay

IF 2.5 4区医学 Q3 VIROLOGY

Archives of Virology Pub Date : 2025-09-23 DOI:10.1007/s00705-025-06407-1

Dimas Arya Abdillah, Takahiro Hiratsuka, Fumiko Matsuyama, Yuki Hattori, Takehisa Soma, Tetsuya Shimoda, Takashi Kato, Hideo Sakai, Masaharu Hisasue, Ariko Miyake, Kazuo Nishigaki

引用次数: 0

Abstract

Feline leukaemia virus subgroup A (FeLV-A) is transmitted among cats, and FeLV subgroups are frequently generated de novo. We investigated the frequency of detection of subgroups using interference assays in 50 cases. FeLV-A infection alone was detected in 38% of the cases, whereas coinfection with both FeLV-A and FeLV-B was observed in 62% of the cases. No cases of FeLV-B infection alone were observed. Cases of coinfection with FeLV-A and FeLV-B showed a higher prevalence than cases of FeLV-A infection alone. The FeLV containing an X region was discovered in two new cases. This study may help to elucidate the mechanism underlying FeLV-B-associated diseases.

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猫白血病病毒亚群使用病毒干扰试验

猫白血病病毒A亚群（FeLV-A）在猫之间传播，FeLV亚群经常重新产生。我们在50例病例中使用干扰法调查了检测亚群的频率。单独感染FeLV-A的病例占38%，而同时感染FeLV-A和FeLV-B的病例占62%。未观察到单独FeLV-B感染病例。合并感染FeLV-A和FeLV-B的病例比单独感染FeLV-A的病例患病率更高。包含X区域的FeLV是在两个新病例中发现的。这项研究可能有助于阐明felv - b相关疾病的机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Archives of Virology 医学-病毒学

CiteScore

5.10

自引率

7.40%

发文量

324

审稿时长

4.5 months

期刊介绍： Archives of Virology publishes original contributions from all branches of research on viruses, virus-like agents, and virus infections of humans, animals, plants, insects, and bacteria. Coverage spans a broad spectrum of topics, from descriptions of newly discovered viruses, to studies of virus structure, composition, and genetics, to studies of virus interactions with host cells, organisms and populations. Studies employ molecular biologic, molecular genetics, and current immunologic and epidemiologic approaches. Contents include studies on the molecular pathogenesis, pathophysiology, and genetics of virus infections in individual hosts, and studies on the molecular epidemiology of virus infections in populations. Also included are studies involving applied research such as diagnostic technology development, monoclonal antibody panel development, vaccine development, and antiviral drug development.Archives of Virology wishes to publish obituaries of recently deceased well-known virologists and leading figures in virology.