IL-assisted strategy for imidazole: A green recipe

IF 1.8 3区化学 Q3 CHEMISTRY, ORGANIC

Synthetic Communications Pub Date : 2025-09-17 DOI:10.1080/00397911.2025.2521832

Vaishali (Writing – original draft) , Shubham Sharma (Supervision Writing – review & editing) , Vinod (Conceptualization Investigation Methodology) , Swati Rani (Software Validation Visualization) , Man Vir Singh (Investigation Validation) , Sodeeq Aderotimi Salami (Validation Visualization) , Sobhi M. Gomha (Project administration Supervision)

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引用次数: 0

Abstract

In the current scenario, the use of nature-friendly methods in organic synthesis is regarded as invaluable and irreplaceable. Significant progress has been made in developing more sustainable and eco-friendly approaches for various organic syntheses and transformations. Within the scope of green synthesis, ILs have attracted a lot of interest since their special features fit for sustainable chemistry. Organic synthesis has increasingly utilized ILs as green catalysts and solvents for the development of countless heterocycles. Among these, imidazole is recognized as a highly valuable and preferred heterocyclic motif. It presents interesting chances for finding ideal structures in the synthesis of synthetic compounds with possible therapeutic uses and other major prospects. A diverse array of ILs has been successfully exploited toward the development of imidazoles. Therefore, this review article offers a thorough review of current studies on the function of ecologically safe ILs in producing a wide range of valuable imidazoles.

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il辅助咪唑的策略：绿色配方

在目前的情况下，在有机合成中使用对自然友好的方法被认为是非常宝贵和不可替代的。在为各种有机合成和转化开发更可持续和更环保的方法方面取得了重大进展。在绿色合成的范围内，ILs由于其适合可持续化学的特性而引起了人们的广泛关注。有机合成越来越多地利用化学偶联化合物作为绿色催化剂和溶剂，开发了无数杂环化合物。其中，咪唑被认为是一个非常有价值和首选的杂环基序。它提供了有趣的机会，找到理想的结构，在合成化合物的可能的治疗用途和其他主要前景。各种各样的il已被成功地用于咪唑的开发。因此，本文综述了生态安全il在生产各种有价值的咪唑方面的研究进展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Synthetic Communications 化学-有机化学

CiteScore

4.40

自引率

4.80%

发文量

156

审稿时长

4.3 months

期刊介绍： Synthetic Communications presents communications describing new methods, reagents, and other synthetic work pertaining to organic chemistry with sufficient experimental detail to permit reported reactions to be repeated by a chemist reasonably skilled in the art. In addition, the Journal features short, focused review articles discussing topics within its remit of synthetic organic chemistry.